The Influence of Antiretroviral Therapy on the QTc Interval in an African Cohort To the Editor—Cardiovascular disease

in human immunodeficiency virus (HIV) infection encompasses a wide range of pathologic entities, including myocardial, pericardial, and endocardial disease, ath-erosclerosis, arrhythmias, and vasculitis. The most common manifestations of HIV-associated heart disease in sub-Saharan Africa are pericarditis, cardiomy-opathy, and pulmonary hypertension [1]. Coronary artery disease, lipodystrophy, and metabolic syndrome, although com-mon in developed countries, are tradi-tionally thought to be less clinically significant problems in the African sub-continent [2]. It is well known that pro