Preliminary Communication The efficacy of antigen-specific immunoadsorption and rebound of

Background. As antigen-specific immunoadsorption (IA) using the Glycosorb-ABO columns is becoming increas-ingly popular in ABO-incompatible (ABOi) transplanta-tion, in this study, we retrospectively investigated the efficacy of Glycosorb-ABO IA in vivo and ex vivo. We also assessed the risk of anti-A/B antibody (ABab) rebound before and after ABOi kidney transplantation. Methods. A protocol for ABOi living donor kidney trans-plantation was used, combining four preoperative and three preemptive postoperative Glycosorb-ABO IAs with rit-uximab and maintenance immunosuppression. ABabs were determined by a haemagglutination titration technique. Results. ABOi kidney transplantation was attempted 45 times and 43 transplantations were performed. Overall patien