Asymmetric Synthesis of Aziridines and Arylalanine Derivatives

Aziridines are useful intermediates for the synthesis of the amino alcohols, amino acids, and nitrogen-containing heterocycles. Though a variety of methods have been developed for the synthesis of aziridines, the simplest one is either the addition of a carbene to an imine or the addition of nitrene to an alkene.1 Recent advances have been made in this area using various Lewis acid catalysts includin