Orthopaedic Surgery The Royal National

Implantation of autologous chondrocytes and matrix autologous chondrocytes are techniques of cartilage repair used in the young adult knee which require harvesting of healthy cartilage and which may cause iatrogenic damage to the joint. This study explores alternative sources of autologous cells. Chondrocytes obtained from autologous bone-marrow-derived cells and those from the damaged cartilage within the lesion itself are shown to be viable alternatives to harvest-derived cells. A sufficient number and quality of cells were obtained by the new techniques and may be suitable for autologous chondrocyte and matrix autologous chondrocyte implantation. Autologous chondrocyte implantation (ACI) and matrix autologous chondrocyte implanta-tion (MACI) are now established techniques for the repair of symptomatic isolated lesions of the articular cartilage in the young adult knee.1-6 The procedure involves two operativ