The Effect of Epidermal Growth Factor, Basic Fibroblast Growth DNA Synthesis of Renal Cell Carcinoma Cell Lines.

has been investigated in a serum free condition. These growth factors atimulated the DNA synthesis of all renal cell carcinoma cell lines dose-dependently. Transforming synthesis of renal cell carcinoma cells. The conditioned medium (which did not include any serum) contained very litle autocrine growth factor for renal cell carcinoma cell itself. These results suggest that paracrine growth factors are mostly related to the growth of renal cell carcinoma cells than autocrine growth factor. The renal cell carcinoma cells, which are the transformed form of renal tubular cells and due to this transformed the renal cell carcinoma cell. INTRODUTION It has been reported that different growth factors are present in the extracts of normal and malignant tissues " 2', blood " and urine4'. These growth factors can stimulate or inhibit cellular differentiation as well as they play important role in cellular proliferation. Growth factor