SHORT COMMUNICATION Effects of consumption of Brussels sprouts on plasma and urinary glutathione S-transferase class-a and-n in humans

2To whom correspondence should be adressed The effects of consumption of glucosinolate-containing Brussels sprouts on plasma and urinary glutathione S-transferase (GST) class-a and-n were investigated. Five male and five female non-smoking volunteers were randomly assigned to two groups in a crossover design. Five persons started on a glucosinolate-free diet (control period), while the other five consumed 300 g of cooked Brussels sprouts per day, at the expense of 300 g of glucosinolate-free vegetables (sprouts period). Dietary regimes were reversed after 1 week. GST levels were measured by enzyme-linked immunoabsorbent assay. At the end of the sprouts period, a significant increase (1.5-fold) in plasma class-a GST levels was observed in males but not in females (control versus sprouts, paired Mest