doi:10.1155/2012/849540 Review Article Temporal Lobe Epilepsy in Children

License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The temporal lobe is a common focus for epilepsy. Temporal lobe epilepsy in infants and children differs from the relatively homo-geneous syndrome seen in adults in several important clinical and pathological ways. Seizure semiology varies by age, and the ictal EEG pattern may be less clear cut than what is seen in adults. Additionally, the occurrence of intractable seizures in the developing brain may impact neurocognitive function remote from the temporal area. While many children will respond favorably to medical therapy, those with focal imaging abnormalities including cortical dysplasia, hippocampal sclerosis, or low-grade tumors are likely to be intractable. Expedient workup and surgical intervention in these medically intractable cases are needed to maximize long-term developmental outcome. 1