ABSTRACT. In his Critique of Pure Reason, Kant (1787/1998) suggested that scientific and humanistic interpretations of human existence can and should be woven into ‘a single philosophical system ’ (p. 695). Yet, Kant was well aware of the profound tension between theoretical analyses of the natural order and practical accounts of our experience as moral agents. In this essay, I argue that the Tree of Knowledge System proposed by Henriques (2003, 2004, 2008) has the scope and conceptual power necessary to account for the emergence of the Kantian tension between theoretical and practical rea-son. Following Kant, however, I maintain that this tension cannot be ade-quately resolved on a theoretical plane. Rather, a holistic account of the cultu...