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Primary mucinous adenocarcinoma of the bladder with signet-ring cells: case report Hospital Professor Edmundo Vasconcelos, São Paulo, Brazil CONTEXT: Primary adenocarcinomas of the bladder are uncommon and usually occur by contiguity with or hematogenic dissemination of other adenocarcinomas such as colorectal, prostate and gynecological tract carcinomas. Mucinous and signet-ring cell histological pat-terns are even rarer and it is often diffi cult to morphologically distinguish them from metastatic colorectal adenocarcinoma. CASE REPORT: We present and discuss a rare case of primary mucinous adenocarcinoma of the bladder with signet-ring cells in a 57-year-old male patient. Other primary sites for the tumor had been excluded and, in the absence of diges-tive tract tumor and for confi rmation that it was a primary bladder tumor, an immunohistochemistry study was performed. KEY WORDS: Urinary bladder. Urinary bladder neoplasms. Mucinous adenocarcinoma. Immuno