European Journal of Case Reports in Internal Medicine DOI: 10.12890/2015_000271 European Journal of Case Reports in Internal Medicine © EFIM 2015 Doi: 10.12890/2015_000271- European Journal of Case Reports in Internal Medicine- © EFIM 2015

Conflicts of Interests: The authors declare that there are no competing interests. Patient's Consent: The authors declare they obtained patient's informed consent. This article is licensed under a Commons Attribution Non-Commercial 4.0 License Kikuchi-Fujimoto's disease is a self-limiting and rare disorder of unknown aetiology. The typical presentation includes fever, cervical lymphadenopathy and night sweats. Consequently, it is part of the differential diagnosis of infectious, lymphoproliferative and connective tissue diseases. Histology demonstrates necrotizing histiocytic lymphadenitis. Treatment is symptomatic with non-steroidal anti-inflammatory agents, although there are reports of corticosteroid use in complicated cases. We present the case of a 23-year-old woman admitted to hospital for fever and cervical lymphadenopathies, and diagnosed with Kikuchi-Fujimoto's disease. LEARNING POINTS • Kikuchi-Fujimoto's disease is an uncommon condition that should be considered in the differential diagnosis of cervical lymphadenopathy. • Lymph node biopsy is required for the diagnosis and to rule out malignancy. • Long-term follow-up is important because of an increased risk for recurrence and for the development of systemic lupus erythematosus