VERIFICATION OF A SET-UP FOR MEASUREMENTS OF ENVIRONMENTAL FINE AND ULTRAFINE PARTICLE RESPIRATORY TRACT DEPOSITION IN HUMANS.

Epidemiology tells us that elevated outdoor particle concentration, e.g. PM2.5 or number of ultrafine particles is associated with increased prevalence of respiratory and cardio-vascular disease in susceptible sub-population (e.g. asthmatics and children). Detailed knowledge of the deposited fraction of inhaled aerosol is needed when determining the dose to the respiratory tract e.g. for differen