ABSTRACT The mechanism(s) by which proteins traverse and exit the Golgi are incompletely understood. Using Aspergillus nidulans hyphae, we show that late Golgi cisternae undergo changes in composition to gradually lose Golgi identity while acquiring post-Golgi RabERAB11 identity. This behavior of late Golgi cisternae is consistent with the cisternal maturation mod-el. Post-Golgi RabERAB11 carriers travel to, and accumulate at, the apex, indicating that fusion is rate limiting for exocytosis. These carriers, which are loaded with kinesin, dynein, and Myo-EMYO5, move on a microtubule-based bidirectional conveyor belt relaying them to actin, which ultimately focuses exocytosis at the apex. Dynein drags RabERAB11 carriers away if engage-ment of...
Vesicular transport of protein and lipid cargo from the endoplasmic reticulum (ER) to cis-Golgi comp...
Integrating the pleomorphic membranes of the intermediate compartment (IC) into the array of Golgi c...
3 páginas 10 figuras -- PAGS nros. 4335-4337Aspergillus nidulans hyphae grow exclusively by apical e...
In this work I investigated the mechanisms governing protein sorting in the Golgi. The cisternal mat...
The Golgi apparatus is a membrane-bound organelle that serves as a central conduit for the processin...
20 p.-2 fig.Cargo passage through the Golgi, albeit an undoubtedly essential cellular function, is a...
21 páginas, 11 figuras -- PAGS nros. 386-406The Aspergillus nidulans Golgi is not stacked. Early and...
<p>A) ER-derived vesicles (beige) fuse with each other to yield the first, most <i>cis</i>, cisterna...
How are proteins transported across the stacked cisternae of the Golgi apparatus? Do they stay withi...
In this work, I addressed issues pertaining to endomembrane transport, compartment organization, and...
AbstractNewly synthesized procollagen type I (PC) assembles into 300 nm rigid, rod-like triple helic...
The order of enzymatic activity across Golgi cisternae is essential for complex molecule biosynthesi...
To describe trafficking of secretory cargo within the Golgi apparatus, the cisternal maturation mode...
ABSTRACT Homotypic membrane tethering by the Golgi reassembly and stacking pro-teins (GRASPs) is req...
Aspergillus nidulans hyphae grow exclusively by apical extension. Golgi equivalents (GEs) labeled wi...
Vesicular transport of protein and lipid cargo from the endoplasmic reticulum (ER) to cis-Golgi comp...
Integrating the pleomorphic membranes of the intermediate compartment (IC) into the array of Golgi c...
3 páginas 10 figuras -- PAGS nros. 4335-4337Aspergillus nidulans hyphae grow exclusively by apical e...
In this work I investigated the mechanisms governing protein sorting in the Golgi. The cisternal mat...
The Golgi apparatus is a membrane-bound organelle that serves as a central conduit for the processin...
20 p.-2 fig.Cargo passage through the Golgi, albeit an undoubtedly essential cellular function, is a...
21 páginas, 11 figuras -- PAGS nros. 386-406The Aspergillus nidulans Golgi is not stacked. Early and...
<p>A) ER-derived vesicles (beige) fuse with each other to yield the first, most <i>cis</i>, cisterna...
How are proteins transported across the stacked cisternae of the Golgi apparatus? Do they stay withi...
In this work, I addressed issues pertaining to endomembrane transport, compartment organization, and...
AbstractNewly synthesized procollagen type I (PC) assembles into 300 nm rigid, rod-like triple helic...
The order of enzymatic activity across Golgi cisternae is essential for complex molecule biosynthesi...
To describe trafficking of secretory cargo within the Golgi apparatus, the cisternal maturation mode...
ABSTRACT Homotypic membrane tethering by the Golgi reassembly and stacking pro-teins (GRASPs) is req...
Aspergillus nidulans hyphae grow exclusively by apical extension. Golgi equivalents (GEs) labeled wi...
Vesicular transport of protein and lipid cargo from the endoplasmic reticulum (ER) to cis-Golgi comp...
Integrating the pleomorphic membranes of the intermediate compartment (IC) into the array of Golgi c...
3 páginas 10 figuras -- PAGS nros. 4335-4337Aspergillus nidulans hyphae grow exclusively by apical e...