Modulation of receptor traffick-ing is critical for controlling neurotransmission. A γ2(R43Q) point mutation on GABA A receptor subunit is linked to epilepsy in human. We recently analyzed the effect of this amino-acid substitution on GABA A receptor traf-ficking and showed that this muta-tion as well as agonist application, both affecting GABA A receptor extracellula
Original article can be found at: http://www.nature.com/bjp/index.html Copyright British Pharmacolog...
Abstract: GABAA receptors have an age-adapted function in the brain. During early development, they ...
OBJECTIVE: Neurosteroids regulate neuronal excitability by potentiating γ-aminobutyric acid type-A r...
A variety of evidence suggested that an imbalance in excitatory and inhibitory neurotransmission cou...
International audienceModulation of receptor traffick- ing is critical for controlling neurotransmis...
Maintaining the correct balance in neuronal activation is of paramount importance to normal brain fu...
A number of epilepsy-causing mutations have recently been identified in the genes of the1,3, and 2 ...
GABAA receptors (GABAARs) are profoundly important for controlling neuronal excitability. Spontaneou...
Given the association of a ?2 mutation (R43Q) with epilepsy and the reduced cell surface expression...
Neurotransmitter receptor trafficking is fundamentally important for synaptic transmission and neura...
GABAA receptors (GABAAR) are the major players in fast inhibitory neurotransmission in the central n...
Epilepsy is a common neurological disorder with a strong hereditary component. A mutation in the α1...
International audienceGABA-gated chloride channels (GABAARs) trafficking is involved in the regulati...
OBJECTIVE: A major goal of epilepsy research is to understand the molecular and functional basis of ...
The gamma-aminobutyric acid type A (GABA(A)) receptor mediates fast inhibitory synaptic transmission...
Original article can be found at: http://www.nature.com/bjp/index.html Copyright British Pharmacolog...
Abstract: GABAA receptors have an age-adapted function in the brain. During early development, they ...
OBJECTIVE: Neurosteroids regulate neuronal excitability by potentiating γ-aminobutyric acid type-A r...
A variety of evidence suggested that an imbalance in excitatory and inhibitory neurotransmission cou...
International audienceModulation of receptor traffick- ing is critical for controlling neurotransmis...
Maintaining the correct balance in neuronal activation is of paramount importance to normal brain fu...
A number of epilepsy-causing mutations have recently been identified in the genes of the1,3, and 2 ...
GABAA receptors (GABAARs) are profoundly important for controlling neuronal excitability. Spontaneou...
Given the association of a ?2 mutation (R43Q) with epilepsy and the reduced cell surface expression...
Neurotransmitter receptor trafficking is fundamentally important for synaptic transmission and neura...
GABAA receptors (GABAAR) are the major players in fast inhibitory neurotransmission in the central n...
Epilepsy is a common neurological disorder with a strong hereditary component. A mutation in the α1...
International audienceGABA-gated chloride channels (GABAARs) trafficking is involved in the regulati...
OBJECTIVE: A major goal of epilepsy research is to understand the molecular and functional basis of ...
The gamma-aminobutyric acid type A (GABA(A)) receptor mediates fast inhibitory synaptic transmission...
Original article can be found at: http://www.nature.com/bjp/index.html Copyright British Pharmacolog...
Abstract: GABAA receptors have an age-adapted function in the brain. During early development, they ...
OBJECTIVE: Neurosteroids regulate neuronal excitability by potentiating γ-aminobutyric acid type-A r...