Background: Mucosal specimens are essential to evaluate compartmentalized immune responses to HIV vaccine candidates and other mucosally targeted investigational products. We studied the acceptability and feasibility of repeated mucosal sampling in East African clinical trial participants at low risk of HIV and other sexually transmitted infections. Methods and Findings: The Kenya AIDS Vaccine Initiative (KAVI) enrolled participants into three Phase 1 trials of preventive HIV candidate vaccines in 2011–2012 at two clinical research centers in Nairobi. After informed consent to a mucosal sub-study, participants were asked to undergo collection of mucosal secretions (saliva, oral fluids, semen, cervico-vaginal and rectal), but could opt out o...
Introduction Optimizing methods for genital specimen collection to accurately characterize mucosal i...
Optimizing methods for genital specimen collection to accurately characterize mucosal immune respons...
Background: Genital mucosae play a key role in protection from STD and HIV infection, due to their i...
Mucosal specimens are essential to evaluate compartmentalized immune responses to HIV vaccine candid...
Because sexual transmission of HIV occurs across mucosal membranes, understanding the immune respons...
Because sexual transmission of HIV occurs across mucosal membranes, understanding the immune respons...
HIV transmission predominantly occurs across mucosal surfaces. Efforts to find an effective and effi...
Because sexual transmission of HIV occurs across mucosal membranes, understanding the immune respons...
There is an urgent need to improve our understanding of the mucosal immuno-pathogenesis of HIV acqui...
International audienceBACKGROUND: Genital mucosae play a key role in protection from STD and HIV inf...
BACKGROUND: Functional analysis of mononuclear leukocytes in the female genital mucosa is essential ...
There is an urgent need to improve our understanding of the mucosal immuno-pathogenesis of HIV acqui...
The spread of HIV continues unabated in the most vulnerable populations of the world. HIV prevention...
Functional analysis of mononuclear leukocytes in the female genital mucosa is essential for understa...
The spread of HIV continues unabated in the most vulnerable populations of the world. HIV prevention...
Introduction Optimizing methods for genital specimen collection to accurately characterize mucosal i...
Optimizing methods for genital specimen collection to accurately characterize mucosal immune respons...
Background: Genital mucosae play a key role in protection from STD and HIV infection, due to their i...
Mucosal specimens are essential to evaluate compartmentalized immune responses to HIV vaccine candid...
Because sexual transmission of HIV occurs across mucosal membranes, understanding the immune respons...
Because sexual transmission of HIV occurs across mucosal membranes, understanding the immune respons...
HIV transmission predominantly occurs across mucosal surfaces. Efforts to find an effective and effi...
Because sexual transmission of HIV occurs across mucosal membranes, understanding the immune respons...
There is an urgent need to improve our understanding of the mucosal immuno-pathogenesis of HIV acqui...
International audienceBACKGROUND: Genital mucosae play a key role in protection from STD and HIV inf...
BACKGROUND: Functional analysis of mononuclear leukocytes in the female genital mucosa is essential ...
There is an urgent need to improve our understanding of the mucosal immuno-pathogenesis of HIV acqui...
The spread of HIV continues unabated in the most vulnerable populations of the world. HIV prevention...
Functional analysis of mononuclear leukocytes in the female genital mucosa is essential for understa...
The spread of HIV continues unabated in the most vulnerable populations of the world. HIV prevention...
Introduction Optimizing methods for genital specimen collection to accurately characterize mucosal i...
Optimizing methods for genital specimen collection to accurately characterize mucosal immune respons...
Background: Genital mucosae play a key role in protection from STD and HIV infection, due to their i...