We have examined the hypothesis that the highly selective recombination of an active mating type locus (MAT) with either HML or HMRa is facilitated by the spatial positioning of relevant sequences within the budding yeast (Saccharomyces cerevisiae) nucleus. However, both position relative to the nuclear envelope (NE) and the subnuclear mobility of fluorescently tagged MAT, HML, or HMR loci are largely identical in haploid a and cells. Irrespective of mating type, the expressed MAT locus is highly mobile within the nuclear lumen, while silent loci move less and are found preferentially near the NE. The perinuclear positions of HMR and HML are strongly compromised in strains lacking the Silent information regulator, Sir4. However, HML, unli...
The HML and HMR loci carry unexpressed copies of MATa and MAT alpha information, and a replica of th...
AbstractHomothallic switching of the mating-type MAT a gene in Saccharomyces cerevisiae results from...
The genetics of the mating-type (MAT) locus have been studied extensively in Saccharomyces cerevisia...
We have examined the hypothesis that the highly selective recombination of an active mating type loc...
We have examined the hypothesis that the highly selective recombination of an active mating type loc...
We have examined the hypothesis that the highly selective recombination of an active mating type loc...
We have examined the hypothesis that the highly selective recombination of an active mating type loc...
We have examined the hypothesis that the highly selective recombination of an active mating type loc...
There are three loci in the yeast Saccharomyces, each containing one of two possible genetic element...
International audienceSaccharomyces mating-type ($MAT$) switching occurs by gene conversion using on...
The organization of eukaryotic genomes is characterized by the presence of distinct euchromatic and ...
Genetic studies have suggested that chromatin structure is involved in repression of the silent mati...
The genome of the yeast Saccharomyces cerevisiae contains three complete copies of the genetic infor...
During homothallic switching of the mating-type (MAT) gene in Saccharomyces cerevisiae, a- or a-spec...
AbstractChromatin boundary activities (BAs) were identified in Saccharomyces cerevisiae by genetic s...
The HML and HMR loci carry unexpressed copies of MATa and MAT alpha information, and a replica of th...
AbstractHomothallic switching of the mating-type MAT a gene in Saccharomyces cerevisiae results from...
The genetics of the mating-type (MAT) locus have been studied extensively in Saccharomyces cerevisia...
We have examined the hypothesis that the highly selective recombination of an active mating type loc...
We have examined the hypothesis that the highly selective recombination of an active mating type loc...
We have examined the hypothesis that the highly selective recombination of an active mating type loc...
We have examined the hypothesis that the highly selective recombination of an active mating type loc...
We have examined the hypothesis that the highly selective recombination of an active mating type loc...
There are three loci in the yeast Saccharomyces, each containing one of two possible genetic element...
International audienceSaccharomyces mating-type ($MAT$) switching occurs by gene conversion using on...
The organization of eukaryotic genomes is characterized by the presence of distinct euchromatic and ...
Genetic studies have suggested that chromatin structure is involved in repression of the silent mati...
The genome of the yeast Saccharomyces cerevisiae contains three complete copies of the genetic infor...
During homothallic switching of the mating-type (MAT) gene in Saccharomyces cerevisiae, a- or a-spec...
AbstractChromatin boundary activities (BAs) were identified in Saccharomyces cerevisiae by genetic s...
The HML and HMR loci carry unexpressed copies of MATa and MAT alpha information, and a replica of th...
AbstractHomothallic switching of the mating-type MAT a gene in Saccharomyces cerevisiae results from...
The genetics of the mating-type (MAT) locus have been studied extensively in Saccharomyces cerevisia...