Research on Alzheimer’s disease (AD) has indicated an association between hormones of the hypothalamic–pituitary– gonadal (HPG) axis and cognitive senescence, indicating that post meno-/andropausal changes in HPG axis hormones are implicated in the neuropathology of AD. Studies of transgenic mice with AD pathologies have led to improved understanding of the pathophysiological processes underlying AD. The aims of this study were to explore whether mRNA-levels of gonadotropin-releasing hormone (Gnrh) and its receptor (Gnrhr) were changed in plaque-bearing Alzheimer’s disease transgenic mice and to investigate whether these levels and amyloid plaque deposition were downregulated by treatment with a gonadotropin-releasing hormone analog (Gnrh-a...
The role of estrogens in Alzheimer's disease (AD) involving β-amyloid (Aβ) generation and plaque for...
Although neuroactive steroids exert neuroprotective actions in different experimental models of neur...
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction...
Research on Alzheimer's disease (AD) has indicated an association between hormones of the hypothalam...
Research on Alzheimer's disease (AD) has indicated an association between hormones of the hypothalam...
Alzheimer\u27s disease is one of the most prevalent and costly neurological diseases in the world. A...
Abstract Biologic sex and gonadal hormones matter in human aging and diseases of aging such as Alzhe...
Recent evidence indicates that, alongside oxidative stress, dysregulation of the cell cycle in neuro...
Decreases in testosterone and 17β-oestradiol (E2) are associated with an increased risk for Alzheime...
AbstractUntil recently, the study of hormonal influences in Alzheimer disease was limited to the rol...
After menopause or ovariectomy (ovx) females have high levels of luteinizing hormone (LH) which may ...
A promising direction in the research on Alzheimer's Disease (AD) is the identification of biomarker...
Normal brain maturation is the result of many structural and molecular changes that can be modulated...
Luteinizing hormone (LH) has recently been localized to extrapituitary regions of the brain includin...
Background: Alzheimer disease (AD) is clinically characterized by progressive memory loss, impairmen...
The role of estrogens in Alzheimer's disease (AD) involving β-amyloid (Aβ) generation and plaque for...
Although neuroactive steroids exert neuroprotective actions in different experimental models of neur...
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction...
Research on Alzheimer's disease (AD) has indicated an association between hormones of the hypothalam...
Research on Alzheimer's disease (AD) has indicated an association between hormones of the hypothalam...
Alzheimer\u27s disease is one of the most prevalent and costly neurological diseases in the world. A...
Abstract Biologic sex and gonadal hormones matter in human aging and diseases of aging such as Alzhe...
Recent evidence indicates that, alongside oxidative stress, dysregulation of the cell cycle in neuro...
Decreases in testosterone and 17β-oestradiol (E2) are associated with an increased risk for Alzheime...
AbstractUntil recently, the study of hormonal influences in Alzheimer disease was limited to the rol...
After menopause or ovariectomy (ovx) females have high levels of luteinizing hormone (LH) which may ...
A promising direction in the research on Alzheimer's Disease (AD) is the identification of biomarker...
Normal brain maturation is the result of many structural and molecular changes that can be modulated...
Luteinizing hormone (LH) has recently been localized to extrapituitary regions of the brain includin...
Background: Alzheimer disease (AD) is clinically characterized by progressive memory loss, impairmen...
The role of estrogens in Alzheimer's disease (AD) involving β-amyloid (Aβ) generation and plaque for...
Although neuroactive steroids exert neuroprotective actions in different experimental models of neur...
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction...