REVIEW Overview of neurosarcoidosis: recent advances

system disease of unknown etiology. Most often the dis-ease affects lungs and mediastinal lymph nodes, but it may occur in other organs. Neurosarcoidosis (NS) more com-monly occurs with other sarcoidosis forms, in 1 % of cases it involves only nervous system. Symptomatic NS occurs but on autopsy study up to 25 % of cases are confirmed. NS can affect central nervous system: the brain, spinal cord and peripheral nerves, and muscles. The diagnosis of neurosarcoidosis facilitates diagnostic criteria: histopa-thological, imaging and cerebrospinal fluid examination, and clinical symptoms. At present, there are no set stan-dards for treatment of patients suffering from NS. Early therapy of symptomatic patients is recommended. Corti-costeroids still are the first line of treatment for NS patients. In cases of steroids resistance, lack of their effectiveness or existence of contraindication to their use, immunosuppressant treatment is recommended. The latest NS algorithm with immunosuppressive treatment is discussed