Reconstitution of the ERG Gene Expression Network Reveals New Biomarkers and Therapeutic Targets in ERG Positive Prostate Tumors

Open Access ERG Expression Levels in Prostate Tumors Reflect Functional Status of the Androgen Receptor (AR) as a Consequence of Fusion of ERG with AR Regulated Gene Promoters

Albert Dobi
Bungo Furusato
Syed Shaheduzzaman
Yongmei Chen
Maryanne Vahey
Timothy Nydam
Isabell A. Sesterhenn
David G. Mcleod
Gyorgy Petrovics
Shiv Srivastava

September 2016

Abstract: Expression of the ERG proto-oncogene, is activated in 50-70 % of prostate tumors by androg...

The oncogenic transcription factor ERG represses the transcription of the tumour suppressor gene PTEN in prostate cancer cells

Adamo, Patricia
Porazinski, Sean
Rajatileka, Shavanthi
Jumbe, Samantha
Hagen, Rachel
Cheung, Man Kim
Wilson, Ian D
Ladomery, Michael

November 2017

The Effect of Tumor Microenvironment on Autophagy and Sensitivity to Targeted Therapy in EGFR-Mutated

Lung Adenocarcinoma
Yuan-yuan Li
Sze-kwan Lam
Chun-yan Zheng
James Chung-man Ho

November 2015

Research Article ERG Protein Expression Is of Limited Prognostic Value in Men with Localized Prostate Cancer

Isrn Urology
Liang Hong Teng
Cheng Wang
Michael Dolph
Bryan Donnelly
Tarek A. Bismar

January 2013

License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...

The Role of ERG Gene in Prostate Cancer

Zachariah, Sharon

January 2021

The second most prevalent cancer among men with a 5-year survival rate of 30%, prostate cancer is a ...

The oncogene ERG: A key factor in prostate cancer

Adamo, Patricia
Ladomery, Michael
Adamo, P.
Ladomery, M. R.

January 2016

An investigation into the role of the transcription factor ERG and its regulation of the members of the insulin-growth factor signalling pathway in prostate cancer

Adamo, Patricia Maria

January 2013

Recently the fusion gene TMPRSS2-ERG has been highlighted as a cancer-specific event in prostate car...

Development of ERG inhibitors as potential drugs for the treatment of metastatic prostate cancer

Roshan-Moniri, Mani

January 2021

Prostate cancer is one of the leading causes of cancer-related death in men worldwide. If diagnosed ...

Overexpression Inhibits Tumor Growth of Prostate Cancer In Vivo

Jinlong Li
Jie Luo
Dongsheng Gu
Feilong Jie
Nana Pei
Andrew Li
Xinglu Chen
Hongyan Du
Baihong Chen
Weiwang Gu
Colin Sumners
Hongwei Li

August 2016

Characterization of Transcriptional Changes in ERG Rearrangement-Positive Prostate Cancer Identifies the Regulation of Metabolic Sensors Such as Neuropeptide Y

Petra Massoner
Karl G. Kugler
Karin Unterberger
Ruprecht Kuner
Laurin A. J. Mueller
Christof Seifarth
Simone Ecker
Irmgard Verdorfer
Armin Graber

September 2016

ERG gene rearrangements are found in about one half of all prostate cancers. Functional analyses do ...

An oncogenic role for transcription factor ERG in prostate cancer progression: promoting androgen-independent growth and survival.

Sng, Noel Yan Wei.

January 2011

The discovery of recurrent gene fusions between AR-regulated transmembrane protease and ERG has shed...

Integration of ERG gene mapping and gene-expression profiling identifies distinct categories of human prostate cancer

Jhavar, Sameer
Brewer, Daniel
Edwards, Sandra
Kote-Jarai, Zsofia
Attard, Gerhardt
Clark, Jeremy
Flohr, Penny
Christmas, Timothy
Thompson, Alan
Parker, Matthew
Shepherd, Christopher
Stenman, Ulf-Hakan
Marchbank, Tania
Playford, Raymond J.
Woodhouse, Christopher
Ogden, Christopher
Fisher, Cyril
Kovacs, Gyula
Corbishley, Cathy
Jameson, Charles
Norman, Andy
De-Bono, Johann
Bjartell, Anders
Eeles, Rosalind
Cooper, Colin S.

January 2009

OBJECTIVE To integrate the mapping of ERG alterations with the collection of expression microarray (...

Targeting the ERG oncogene with splice-switching oligonucleotides as a novel therapeutic strategy in prostate cancer

Li, L
Hobson, L
Perry, L
Clark, B
Heavey, S
Haider, A
Sridhar, A
Shaw, G
Kelly, J
Freeman, A
Wilson, I
Whitaker, H
Nurmemmedov, E
Oltean, S
Porazinski, S
Ladomery, M

July 2020

This is the author accepted manuscript. The final version is available from Springer Nature via the ...

High-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancer

Vainio, Paula
Mpindi, J.-P.
Kohonen, Pekka
Fey, Vidal
Mirtti, T.
Alanen, K.A.
Perälä, Merja
Kallioniemi, Olli
Iljin, Kristiina

January 2012

Prostate cancer is a heterogeneous group of diseases and there is a need for more efficient and targ...

Overexpression of FGF9 in Prostate Epithelial Cells Augments Reactive Stroma Formation and Promotes Prostate Cancer Progression

Yanqing Huang
Chengliu Jin
Tomoaki Hamana
Junchen Liu
Cong Wang
Lei An
Wallace L

August 2016

Open Access ERG Expression Levels in Prostate Tumors Reflect Functional Status of the Androgen Receptor (AR) as a Consequence of Fusion of ERG with AR Regulated Gene Promoters

Albert Dobi
Bungo Furusato
Syed Shaheduzzaman
Yongmei Chen
Maryanne Vahey
Timothy Nydam
Isabell A. Sesterhenn
David G. Mcleod
Gyorgy Petrovics
Shiv Srivastava

September 2016

Abstract: Expression of the ERG proto-oncogene, is activated in 50-70 % of prostate tumors by androg...

The oncogenic transcription factor ERG represses the transcription of the tumour suppressor gene PTEN in prostate cancer cells

Adamo, Patricia
Porazinski, Sean
Rajatileka, Shavanthi
Jumbe, Samantha
Hagen, Rachel
Cheung, Man Kim
Wilson, Ian D
Ladomery, Michael

November 2017

The Effect of Tumor Microenvironment on Autophagy and Sensitivity to Targeted Therapy in EGFR-Mutated

Lung Adenocarcinoma
Yuan-yuan Li
Sze-kwan Lam
Chun-yan Zheng
James Chung-man Ho

November 2015

Research Article ERG Protein Expression Is of Limited Prognostic Value in Men with Localized Prostate Cancer

Isrn Urology
Liang Hong Teng
Cheng Wang
Michael Dolph
Bryan Donnelly
Tarek A. Bismar

January 2013

License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...

The Role of ERG Gene in Prostate Cancer

Zachariah, Sharon

January 2021

The second most prevalent cancer among men with a 5-year survival rate of 30%, prostate cancer is a ...

The oncogene ERG: A key factor in prostate cancer

Adamo, Patricia
Ladomery, Michael
Adamo, P.
Ladomery, M. R.

January 2016

An investigation into the role of the transcription factor ERG and its regulation of the members of the insulin-growth factor signalling pathway in prostate cancer

Adamo, Patricia Maria

January 2013

Recently the fusion gene TMPRSS2-ERG has been highlighted as a cancer-specific event in prostate car...

Development of ERG inhibitors as potential drugs for the treatment of metastatic prostate cancer

Roshan-Moniri, Mani

January 2021

Prostate cancer is one of the leading causes of cancer-related death in men worldwide. If diagnosed ...

Overexpression Inhibits Tumor Growth of Prostate Cancer In Vivo

Jinlong Li
Jie Luo
Dongsheng Gu
Feilong Jie
Nana Pei
Andrew Li
Xinglu Chen
Hongyan Du
Baihong Chen
Weiwang Gu
Colin Sumners
Hongwei Li

August 2016

Characterization of Transcriptional Changes in ERG Rearrangement-Positive Prostate Cancer Identifies the Regulation of Metabolic Sensors Such as Neuropeptide Y

Petra Massoner
Karl G. Kugler
Karin Unterberger
Ruprecht Kuner
Laurin A. J. Mueller
Christof Seifarth
Simone Ecker
Irmgard Verdorfer
Armin Graber

September 2016

ERG gene rearrangements are found in about one half of all prostate cancers. Functional analyses do ...

An oncogenic role for transcription factor ERG in prostate cancer progression: promoting androgen-independent growth and survival.

Sng, Noel Yan Wei.

January 2011

The discovery of recurrent gene fusions between AR-regulated transmembrane protease and ERG has shed...

Integration of ERG gene mapping and gene-expression profiling identifies distinct categories of human prostate cancer

Jhavar, Sameer
Brewer, Daniel
Edwards, Sandra
Kote-Jarai, Zsofia
Attard, Gerhardt
Clark, Jeremy
Flohr, Penny
Christmas, Timothy
Thompson, Alan
Parker, Matthew
Shepherd, Christopher
Stenman, Ulf-Hakan
Marchbank, Tania
Playford, Raymond J.
Woodhouse, Christopher
Ogden, Christopher
Fisher, Cyril
Kovacs, Gyula
Corbishley, Cathy
Jameson, Charles
Norman, Andy
De-Bono, Johann
Bjartell, Anders
Eeles, Rosalind
Cooper, Colin S.

January 2009

OBJECTIVE To integrate the mapping of ERG alterations with the collection of expression microarray (...

Targeting the ERG oncogene with splice-switching oligonucleotides as a novel therapeutic strategy in prostate cancer

Li, L
Hobson, L
Perry, L
Clark, B
Heavey, S
Haider, A
Sridhar, A
Shaw, G
Kelly, J
Freeman, A
Wilson, I
Whitaker, H
Nurmemmedov, E
Oltean, S
Porazinski, S
Ladomery, M

July 2020

This is the author accepted manuscript. The final version is available from Springer Nature via the ...

High-throughput transcriptomic and RNAi analysis identifies AIM1, ERGIC1, TMED3 and TPX2 as potential drug targets in prostate cancer

Vainio, Paula
Mpindi, J.-P.
Kohonen, Pekka
Fey, Vidal
Mirtti, T.
Alanen, K.A.
Perälä, Merja
Kallioniemi, Olli
Iljin, Kristiina

January 2012

Prostate cancer is a heterogeneous group of diseases and there is a need for more efficient and targ...

Overexpression of FGF9 in Prostate Epithelial Cells Augments Reactive Stroma Formation and Promotes Prostate Cancer Progression

Yanqing Huang
Chengliu Jin
Tomoaki Hamana
Junchen Liu
Cong Wang
Lei An
Wallace L

August 2016

Open Access ERG Expression Levels in Prostate Tumors Reflect Functional Status of the Androgen Receptor (AR) as a Consequence of Fusion of ERG with AR Regulated Gene Promoters

Albert Dobi
Bungo Furusato
Syed Shaheduzzaman
Yongmei Chen
Maryanne Vahey
Timothy Nydam
Isabell A. Sesterhenn
David G. Mcleod
Gyorgy Petrovics
Shiv Srivastava

September 2016

Abstract: Expression of the ERG proto-oncogene, is activated in 50-70 % of prostate tumors by androg...

The oncogenic transcription factor ERG represses the transcription of the tumour suppressor gene PTEN in prostate cancer cells

Adamo, Patricia
Porazinski, Sean
Rajatileka, Shavanthi
Jumbe, Samantha
Hagen, Rachel
Cheung, Man Kim
Wilson, Ian D
Ladomery, Michael

November 2017

The Effect of Tumor Microenvironment on Autophagy and Sensitivity to Targeted Therapy in EGFR-Mutated

Lung Adenocarcinoma
Yuan-yuan Li
Sze-kwan Lam
Chun-yan Zheng
James Chung-man Ho

November 2015

Reconstitution of the ERG Gene Expression Network Reveals New Biomarkers and Therapeutic Targets in ERG Positive Prostate Tumors

Abstract

Extracted data

Reconstitution of the ERG Gene Expression Network Reveals New Biomarkers and Therapeutic Targets in ERG Positive Prostate Tumors

Abstract

Extracted data

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