with Crohn’s disease

A recent prospective multicenter study by Weinstock et al indicated that restless legs syndrome (RLS) is commonly found in patients with Crohn’s disease (CD), with incidence and prevalence rates of 42.7 % and 30.2 % respectively [1]. This disease entity, even though it has a great impact on both sleep disturbances and on quality of life, has not yet been thoroughly investigated in patients with CD. RLS is a common, but significantly underestimated and misdiagnosed, neurological disorder affecting about 5-10 % of the general population in Europe and the United States [2]. It is mainly characterized by a sense of discomfort and an urge to move focused on the legs; the diagnosis can be set with the standard diagnostic criteria that have been established from the International RLS Study Group since 1995 (Table 1). Although iron deficiency anemia is considered as a sec