Add to ORKGAttribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. GalNAc-T1, a key candidate of GalNac-transferases genes family that is involved in mucin-type O-linked glycosylation pathway, is expressed in most biological tissues and cell types. Despite the reported association of GalNAc-T1 gene mutations with human disease susceptibility, the comprehensive computational analysis of coding, noncoding and regulatory SNPs, and their functional impacts on protein level, still remains unknown. Therefore, sequence- and structure-based computational tools were employed to screen the entire listed coding SNPs of GalNAc-T1 gene in order to identify and characterize the...
Background: Galectin-3 protein, an S-type lectin, is encoded by LGALS3 gene. It consists of carbohyd...
With the completion of the human genome project at the beginning of the 21st century, the biological...
AbstractBackground and aimsNon-synonymous (ns)SNPs represent typical genetic variations that may pot...
GalNAc-T1, a key candidate of GalNac-transferases genes family that is involved in mucin-type O-link...
Aberrant glycosylation by N-acetylgalactosaminyl transferases (GALNTs) is a well-described pathologi...
Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, p...
With the rapid development and decreasing cost of sequencing technologies, more and more novel genet...
The family of polypeptide N-acetylgalactosamine (GalNAc) transferases (GalNAc-Ts) orchestrates the i...
Background: Genome-wide association studies of common diseases for common, low penetrance causal var...
<div><p>Background</p><p>α-Thalassemia (α-thal) is a genetic disorder caused by the substitution of ...
AbstractSingle-nucleotide polymorphisms (SNPs) play a major role in the understanding of the genetic...
Association studies of SNPs have become very important in determining how genetic variants are linke...
ABSTRACT: Next-generation sequencing (NGS) technolo-gies are yielding ever higher volumes of human g...
Single nucleotide polymorphisms (SNPs) are often associated with conferring risk for disease, and ar...
Background and aims: Non-synonymous (ns)SNPs represent typical genetic variations that may potential...
Background: Galectin-3 protein, an S-type lectin, is encoded by LGALS3 gene. It consists of carbohyd...
With the completion of the human genome project at the beginning of the 21st century, the biological...
AbstractBackground and aimsNon-synonymous (ns)SNPs represent typical genetic variations that may pot...
GalNAc-T1, a key candidate of GalNac-transferases genes family that is involved in mucin-type O-link...
Aberrant glycosylation by N-acetylgalactosaminyl transferases (GALNTs) is a well-described pathologi...
Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, p...
With the rapid development and decreasing cost of sequencing technologies, more and more novel genet...
The family of polypeptide N-acetylgalactosamine (GalNAc) transferases (GalNAc-Ts) orchestrates the i...
Background: Genome-wide association studies of common diseases for common, low penetrance causal var...
<div><p>Background</p><p>α-Thalassemia (α-thal) is a genetic disorder caused by the substitution of ...
AbstractSingle-nucleotide polymorphisms (SNPs) play a major role in the understanding of the genetic...
Association studies of SNPs have become very important in determining how genetic variants are linke...
ABSTRACT: Next-generation sequencing (NGS) technolo-gies are yielding ever higher volumes of human g...
Single nucleotide polymorphisms (SNPs) are often associated with conferring risk for disease, and ar...
Background and aims: Non-synonymous (ns)SNPs represent typical genetic variations that may potential...
Background: Galectin-3 protein, an S-type lectin, is encoded by LGALS3 gene. It consists of carbohyd...
With the completion of the human genome project at the beginning of the 21st century, the biological...
AbstractBackground and aimsNon-synonymous (ns)SNPs represent typical genetic variations that may pot...