pe as ici 4, termed 4qA161 [8,9], the key feature of which is the activities, DUX4 is the key molecular target in the devel-Bosnakovski et al. Skeletal Muscle 2014, 4:4 http://www.skeletalmusclejournal.com/content/4/1/4and transmission of a signal through one or more cellChurch St. S.E, Minneapolis, MN 55455, USA Full list of author information is available at the end of the articlepresence of a polyadenylation signal [10,11]. This indicates that an mRNA transcript produced from D4Z4 must be opment of a pharmacological treatment for FSHD. We have previously developed a cell line in which DUX4 can be induced to various levels of expression with doxy-cycline (dox) [13]. Here, we use the cell death phenotype as a screening tool to identify com...
International audienceFacioscapulohumeral muscular dystrophy (FSHD) is a dominant disease linked to ...
Thesis (Ph.D.)--University of Washington, 2011Double homeobox 4 (DUX4) is a candidate disease gene f...
Facioscapulohumeral muscular dystrophy (FSHD) is believed to be caused by aberrant expression of dou...
BACKGROUND: Facioscapulohumeral muscular dystrophy (FSHD) is caused by epigenetic alterations at...
Facioscapulohumeral muscular dystrophy (FSHD) is linked to deletions in 4q35 within the D4Z4 repeat ...
First step towards developing a targeted therapy for any diseases is to generate model system for st...
Facioscapulohumeral muscular dystrophy is a genetically dominant, currently untreatable muscular dys...
Facioscapulohumeral dystrophy (FSHD) is associated with the upregulation of the DUX4 transcription f...
Facioscapulohumeral muscular dystrophy (FSHD) is a muscle degenerative disease that disproportionall...
Facioscapulohumeral muscular dystrophy (FSHD) patients carry contractions of the D4Z4-tandem repeat ...
Rising evidence, which is in agreement with our preliminary data, suggests that D4Z4 including DUX4 ...
FSHD is characterized by the misexpression of DUX4 in skeletal muscle. Although DUX4 upregulation is...
Facioscapulohumeral muscular dystrophy (FSHD) is a dominant disease linked to contractions of the D4...
Facioscapulohumeral muscular dystrophy (FSHD) is caused by an unusual deletion with neomorphic activ...
International audienceFacioscapulohumeral muscular dystrophy (FSHD) patients carry contractions of t...
International audienceFacioscapulohumeral muscular dystrophy (FSHD) is a dominant disease linked to ...
Thesis (Ph.D.)--University of Washington, 2011Double homeobox 4 (DUX4) is a candidate disease gene f...
Facioscapulohumeral muscular dystrophy (FSHD) is believed to be caused by aberrant expression of dou...
BACKGROUND: Facioscapulohumeral muscular dystrophy (FSHD) is caused by epigenetic alterations at...
Facioscapulohumeral muscular dystrophy (FSHD) is linked to deletions in 4q35 within the D4Z4 repeat ...
First step towards developing a targeted therapy for any diseases is to generate model system for st...
Facioscapulohumeral muscular dystrophy is a genetically dominant, currently untreatable muscular dys...
Facioscapulohumeral dystrophy (FSHD) is associated with the upregulation of the DUX4 transcription f...
Facioscapulohumeral muscular dystrophy (FSHD) is a muscle degenerative disease that disproportionall...
Facioscapulohumeral muscular dystrophy (FSHD) patients carry contractions of the D4Z4-tandem repeat ...
Rising evidence, which is in agreement with our preliminary data, suggests that D4Z4 including DUX4 ...
FSHD is characterized by the misexpression of DUX4 in skeletal muscle. Although DUX4 upregulation is...
Facioscapulohumeral muscular dystrophy (FSHD) is a dominant disease linked to contractions of the D4...
Facioscapulohumeral muscular dystrophy (FSHD) is caused by an unusual deletion with neomorphic activ...
International audienceFacioscapulohumeral muscular dystrophy (FSHD) patients carry contractions of t...
International audienceFacioscapulohumeral muscular dystrophy (FSHD) is a dominant disease linked to ...
Thesis (Ph.D.)--University of Washington, 2011Double homeobox 4 (DUX4) is a candidate disease gene f...
Facioscapulohumeral muscular dystrophy (FSHD) is believed to be caused by aberrant expression of dou...