Research Article

Copyright © 2013 Yasuyuki Nakamura et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Objective. Despite considerable study, the relevance of leptin and adiponectin for atherosclerosis development is still unsettled. We investigated relations of serum leptin and adiponectin to serum C-reactive protein (CRP), using the INTERLIPID dataset on Japanese emigrants living inHawaii and Japanese in Japan.Design andMethods. Serum leptin, adiponectin, andCRPweremeasured by standardizedmethods inmen andwomen of ages 40 to 59 years from two population samples, one Japanese-American inHawaii (83 men, 89 women) and the other Japanese in central Japan (111 men, 104 women). Participants with CRP>10mg/L were excluded. Results. Sex-specific multiple linear regression analyses, with log-transformed leptin and adiponectin (log-leptin, log-adipo), sit