Add to ORKGBackground & Aim: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in both adult and children. Currently there are no reliable methods to determine disease severity, monitor disease progression, or efficacy of therapy, other than an invasive liver biopsy. Design: Choline Deficient L-Amino Acid (CDAA) and high fat diets were used as physiologically relevant mouse models of NAFLD. Circulating extracellular vesicles were isolated, fully characterized by proteomics and molecular analyses and compared to control groups. Liver-related microRNAs were isolated from purified extracellular vesicles and liver specimens. Results:We observed statistically significant differences in the level of extracellular vesicles...
Once thought to be a benign accumulation of hepatic fat, non-alcoholic fatty liver disease (NAFLD) i...
Extracellular vesicles (EVs) are membrane-bound endogenous nanoparticles released by the majority of...
Multi-omics multi-tissue data are used to interpret genome-wide association study results from mice ...
<div><p>Background & Aim</p><p>Nonalcoholic fatty liver disease (NAFLD) is the most common chronic l...
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in both adult and ...
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease around th...
Background: Hepatocellular carcinoma (HCC) is the most common malignant tumor of the liver. Non-alco...
In recent years, the global burden of obesity and diabetes has seen a parallel rise in other metabol...
Cell-to-cell communication is a fascinating process that is essential for maintaining tissue and who...
Background/Aim: Emerging evidence suggests that microRNA (miRNA) mediated gene regulation influences...
Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease ...
Extracellular vesicles (EVs) are membrane-derived vesicles released by a variety of cell types, incl...
Acute and chronic liver damage are associated with severe pathogenic conditions, including loss of f...
Microarray analyses and molecular profiling of steatosis induction in immortalized human hepatocytes...
Extracellular vesicles (EVs) released during cell stress, or demise, can contain a barcode of the ce...
Once thought to be a benign accumulation of hepatic fat, non-alcoholic fatty liver disease (NAFLD) i...
Extracellular vesicles (EVs) are membrane-bound endogenous nanoparticles released by the majority of...
Multi-omics multi-tissue data are used to interpret genome-wide association study results from mice ...
<div><p>Background & Aim</p><p>Nonalcoholic fatty liver disease (NAFLD) is the most common chronic l...
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in both adult and ...
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease around th...
Background: Hepatocellular carcinoma (HCC) is the most common malignant tumor of the liver. Non-alco...
In recent years, the global burden of obesity and diabetes has seen a parallel rise in other metabol...
Cell-to-cell communication is a fascinating process that is essential for maintaining tissue and who...
Background/Aim: Emerging evidence suggests that microRNA (miRNA) mediated gene regulation influences...
Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease ...
Extracellular vesicles (EVs) are membrane-derived vesicles released by a variety of cell types, incl...
Acute and chronic liver damage are associated with severe pathogenic conditions, including loss of f...
Microarray analyses and molecular profiling of steatosis induction in immortalized human hepatocytes...
Extracellular vesicles (EVs) released during cell stress, or demise, can contain a barcode of the ce...
Once thought to be a benign accumulation of hepatic fat, non-alcoholic fatty liver disease (NAFLD) i...
Extracellular vesicles (EVs) are membrane-bound endogenous nanoparticles released by the majority of...
Multi-omics multi-tissue data are used to interpret genome-wide association study results from mice ...