Add to ORKGCopyright © 2013 Alexandra E. Schreiner et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Astrocytes express the sodium-dependent glutamate transportersGLAST andGLT-1, which are critical tomaintain low extracellular glutamate concentrations. Here, we analyzed changes in their expression and function following a mechanical lesion in the CA1 area of organotypic hippocampal slices. 6-7 days after lesion, a glial scar had formed along the injury site, containing strongly activated astrocytes with increased GFAP and S10
Astrocyte activation is a hallmark of central nervous system injuries resulting in glial scar format...
Although glial cells have been traditionally viewed as supportive partners of neurons, studies of th...
It has been estimated that traumatic brain injury (TBI) costs the U.S. economy over $60 billion a ye...
Reactive gliosis is a process triggered in astrocytes after traumatic injury, yet the exact conseque...
Copyright © 2015 Montserrat Batlle et al. This is an open access article distributed under the Creat...
Astrocytes play an important role in physiological, metabolic, and structural functions, and when im...
licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that th...
The GLT-1 and GLAST astroglial transporters are the glutamate transporters mainly involved in mainta...
The brain is an extremely complex organ composed of neuronal and non-neuronal cells working en conce...
Traumatic brain injury is followed by increased extracellular glutamate concentration. Uptake of glu...
Copyright © 2015 Cristiane Batassini et al. This is an open access article distributed under the Cre...
<p>(A1–A2) In the normal brain, GFAP staining (brown) showed slim astrocyte morphology and HE staini...
Neurotrauma or focal brain ischemia are known to trigger molecular and structural responses in the u...
It has been estimated that traumatic brain injury (TBI) costs the U.S. economy over $60 billion a ye...
For decades, astrocytes have been regarded as passive partners of neurons in central nervous system ...
Astrocyte activation is a hallmark of central nervous system injuries resulting in glial scar format...
Although glial cells have been traditionally viewed as supportive partners of neurons, studies of th...
It has been estimated that traumatic brain injury (TBI) costs the U.S. economy over $60 billion a ye...
Reactive gliosis is a process triggered in astrocytes after traumatic injury, yet the exact conseque...
Copyright © 2015 Montserrat Batlle et al. This is an open access article distributed under the Creat...
Astrocytes play an important role in physiological, metabolic, and structural functions, and when im...
licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that th...
The GLT-1 and GLAST astroglial transporters are the glutamate transporters mainly involved in mainta...
The brain is an extremely complex organ composed of neuronal and non-neuronal cells working en conce...
Traumatic brain injury is followed by increased extracellular glutamate concentration. Uptake of glu...
Copyright © 2015 Cristiane Batassini et al. This is an open access article distributed under the Cre...
<p>(A1–A2) In the normal brain, GFAP staining (brown) showed slim astrocyte morphology and HE staini...
Neurotrauma or focal brain ischemia are known to trigger molecular and structural responses in the u...
It has been estimated that traumatic brain injury (TBI) costs the U.S. economy over $60 billion a ye...
For decades, astrocytes have been regarded as passive partners of neurons in central nervous system ...
Astrocyte activation is a hallmark of central nervous system injuries resulting in glial scar format...
Although glial cells have been traditionally viewed as supportive partners of neurons, studies of th...
It has been estimated that traumatic brain injury (TBI) costs the U.S. economy over $60 billion a ye...