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Measles is a highly infectious and contagious disease of the respiratory system caused by Morbilivirus which belongs to family Paramyxoviridae (Hashiguchi et al., 2011). The disease is a common cause of childhood morbidity and mortality across the globe, particularly in de-veloping countries and has been characterized by high fever, cough, conjunctivitis, coryza, malaise and maculopapular rash along with erythematous patches throughout the body (El-lison, 1931; Yanagi et al., 2006; Fazlalipour et al., 2008). Measles infection has been con-trolled by introduction of live attenuated measles vaccine in United States and Europe (Gin-dler et al., 2004). However, measles is still affecting the developing countries due to insuffi-cient coverage and improper handling of vaccines (Poland and Jocobson, 1994; Muscat et al., 2009). Historically, immunization against vaccine preventable diseases (VPDs) in children has been started by WHO in 1974, and it was initiated in Pakistan during 1978 (Ali, 2000; Bugvi et al., 2014). In general the vaccine coverage against VPDs in Pakistan ranged between 56 to 88 % which significantly varied among various Provinces (Sheikh et al., 2011). Recently, increased number of measles outbreaks with high morbidity and mortality has been observed in various regions of Pakistan during recent years (Khan and Khan, 2012