Research Article Association of Apolipoprotein A5 Gene −1131T>C Polymorphism with the Risk of Metabolic Syndrome in Korean Subjects

License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. We assessed the associations between the APOA5 −1131T>C polymorphism and lipid parameters and other risk factors of the metabolic syndrome in Korean subjects. A total of 2,901 participants from 20 oriental medical hospitals in Korea were enrolled between 2006 and 2011. According to the modi�ed �ational Cholesterol Education ProgramAdult Treatment Panel III de�nitions, subjects were classi�ed into the metabolic syndrome group and control group. e APOA5 −1131T>C genotype was signi�cantly associated with serum high-density lipoprotein cholesterol levels (effect = − 1.700mg/dL