Several human small heat shock proteins (sHsps) are phosphorylated oligomeric chaperones that enhance stress resistance. They are characterized by their ability to interact and form polydispersed hetero-oligomeric complexes. We have analyzed the cellular consequences of the stable expression of either wild type HspB5 or its cataracts and myopathies inducing R120G mutant in growing and oxidative stress treated HeLa cells that originally express only HspB1. Here, we describe that wild type and mutant HspB5 induce drastic and opposite effects on cell morphology and oxidative stress resistance. The cellular distribution and phosphorylation of these polypeptides as well as the oligomerization profile of the resulting hetero-oligomeric complexes ...
Congenital mutations in human small heat shock protein HSPB1 (HSP27) have been linked to Charcot-Mar...
The small heat shock proteins (sHSP) comprise 10 members in mammals where they are called the HspB p...
The family of small heat shock proteins (sHsp) is composed of 10 members in mammals, four of which a...
Several human small heat shock proteins (sHsps) are phosphorylated oligomeric chaperones that enhanc...
<div><p>Several human small heat shock proteins (sHsps) are phosphorylated oligomeric chaperones tha...
<div><p>HSPB5 (also called αB-crystallin) is a ubiquitously expressed small heat shock protein. Muta...
HSPB5 (also called αB-crystallin) is a ubiquitously expressed small heat shock protein. Mu-tations i...
The family of the human small Heat Shock Proteins (HSPBs) consists of ten members of chaperones (HSP...
The small heat shock proteins (sHsps) from human (Hsp27) and mouse (Hsp25) form large oligomers whic...
The small heat shock proteins (sHsps) from human (Hsp27) and mouse (Hsp25) form large oligomers whic...
Congenital mutations in human small heat shock protein HSPB1 (HSP27) have been linked to Charcot-Mar...
Thesis (Ph.D.)--University of Washington, 2022Small heat shock proteins (sHSPs) are molecular chaper...
AbstractSmall heat shock proteins (sHsps) are conserved across species and are important in stress t...
The pathogenesis of neurodegenerative diseases, such as Alzheimer’s disease and amyotrophic lateral ...
Mutations of HSPB5 (also known as CRYAB or αB-crystallin), a bona fide heat shock protein and molecu...
Congenital mutations in human small heat shock protein HSPB1 (HSP27) have been linked to Charcot-Mar...
The small heat shock proteins (sHSP) comprise 10 members in mammals where they are called the HspB p...
The family of small heat shock proteins (sHsp) is composed of 10 members in mammals, four of which a...
Several human small heat shock proteins (sHsps) are phosphorylated oligomeric chaperones that enhanc...
<div><p>Several human small heat shock proteins (sHsps) are phosphorylated oligomeric chaperones tha...
<div><p>HSPB5 (also called αB-crystallin) is a ubiquitously expressed small heat shock protein. Muta...
HSPB5 (also called αB-crystallin) is a ubiquitously expressed small heat shock protein. Mu-tations i...
The family of the human small Heat Shock Proteins (HSPBs) consists of ten members of chaperones (HSP...
The small heat shock proteins (sHsps) from human (Hsp27) and mouse (Hsp25) form large oligomers whic...
The small heat shock proteins (sHsps) from human (Hsp27) and mouse (Hsp25) form large oligomers whic...
Congenital mutations in human small heat shock protein HSPB1 (HSP27) have been linked to Charcot-Mar...
Thesis (Ph.D.)--University of Washington, 2022Small heat shock proteins (sHSPs) are molecular chaper...
AbstractSmall heat shock proteins (sHsps) are conserved across species and are important in stress t...
The pathogenesis of neurodegenerative diseases, such as Alzheimer’s disease and amyotrophic lateral ...
Mutations of HSPB5 (also known as CRYAB or αB-crystallin), a bona fide heat shock protein and molecu...
Congenital mutations in human small heat shock protein HSPB1 (HSP27) have been linked to Charcot-Mar...
The small heat shock proteins (sHSP) comprise 10 members in mammals where they are called the HspB p...
The family of small heat shock proteins (sHsp) is composed of 10 members in mammals, four of which a...