RESEARCH ARTICLE Impact of Body Mass Index on In-Hospital Complications in Patients Undergoing Percutaneous Coronary Intervention in a Japanese Real-World Multicenter Registry

Background Obesity is associated with advanced cardiovascular disease. However, some studies have reported the “obesity paradox ” after percutaneous coronary intervention (PCI). The relation-ship between body mass index (BMI) and clinical outcomes after PCI has not been thor-oughly investigated, especially in Asian populations. Methods We studied 10,142 patients who underwent PCI at 15 Japanese hospitals participating in the JCD-KICS registry from September 2008 to April 2013. Patients were divided into four groups according to BMI: underweight, BMI <18.5 (n=462); normal, BMI18.5 and <25.0 (n=5,945); overweight, BMI25.0 and <30.0 (n=3,100); and obese, BMI30.0 (n=635). Results Patients with a high BMI were significantly younger (p<0.001) and had a higher incidence of coronary risk factors such as hypertension (p<0.001), hyperlipidemia (p<0.001), diabetes mellitus (p<0.001), and current smoking (p<0.001), than those with a low BMI. Importantly, pa