Iranian Red Crescent Medical Journal Iran Red Crescent Med J 2011; 13(6):392-397 ©Iranian Red Crescent Medical Journal ORIGINAL ARTICLE Graft Survival Rate of Renal Transplantation: A Single Center Experience, (1999-2009)

Background: Renal transplantation is the best option for treatment of the end-stage renal diseases and has more advantages than dialysis. The objective of this study is to determine the ten-year graft survival rate of renal transplantation and its associated factors in patients who have been transplanted from March 1999 to March 2009 in Nemazee Hospital Transplantation Center. Methods: This is a historical cohort study of 1356 renal transplantation carried out during 1999 to 2009. Kaplan-Meier method was used to determine the survival rate, log rank test to compare survival curves, and Cox regres-sion model to determine hazard ratios and for modeling of variables affecting survival. Results: The 1, 3, 5, 7 and 10 years graft survival rates were 96.6, 93.7, 88.9, 87.1 and 85.5 percent, respective-ly. Cox regression model revealed that the donor source and creatinine level at discharge were effective factors in graft survival rate in renal transplantation. Conclusion: Our study showed that 10 year graft survival rate for renal transplantation in Nemazee Hospital Transplantation Center was 85.5 % and graft survival rate was significantly related to recipients and donor’s age, donor source and creatinine level at discharge. Our experience in renal transplantation survival rate indicates a success rate comparable to those noted in other reports