RESEARCH Impact of 18F-FDG PET/CT r

Full list of author information is available at the end of the articlethe diagnosis of gynaecologic cancer. These conventional imaging modalities present a high sensitivity, specificity and accuracy in the primary staging of the disease. How-ever, the accuracy and specificity of these techniques for the detection of pelvic tumor recurrences or postsurgical residual disease remains low owing to limitations in dis-tinguishing disease from postsurgical changes [1,2]. CT and MRI may be used for target volume delineation in cently, 18 fluorodeoxyglucose ( F-FDG) positron emis-sion tomography – computed tomography (PET/CT) has been recognized as a valuable tool for the diagnosis of pri-mary and recurrent gynaecological cancer enabling the optimization of RT treatment planning [3,4]. The objective of this study is to assess the role of 18F-FDG PET/CT based target volume delineation in recurrent or post-surgical residual gynaecologic cancer. We compared the gross tumor volume (GTV) defined manually by four experienced radiation oncologists using contrast-enhanced CT and fused 18F-FDG PET/CT images, as wel