OBJECTIVE—To assess the long-term effects of an intensive lifestyle intervention on physical function using a randomized post-test design in the Look AHEAD trial. METHODS—Overweight and obese (BMI ≥25 kg/m2) middle-aged and older adults (aged 45–76 years at enrollment) with type 2 diabetes (n=964) at four clinics in Look AHEAD, a trial evaluating an intensive lifestyle intervention (ILI) designed to achieve weight loss through caloric restriction and increased physical activity compared to diabetes support and education (DSE), underwent standardized assessments of performance-based physical function including an expanded short physical performance battery (SPPBexp), 20-m and 400-m walk, and grip and kne
Aims/hypothesis The aim of this study was to evaluate the effects on diabetic peripheral neuropathy ...
OBJECTIVE: To assess the relative impact of an intensive lifestyle intervention (ILI) on use and cos...
The primary aims of this paper were (1) to evaluate the influence of intensive lifestyle weight loss...
Objective—To evaluate 8-year weight losses achieved with intensive lifestyle intervention (ILI) in t...
Background. Compared with adults without type 2 diabetes mellitus, those with the disease experience...
OBJECTIVEdRates of severe obesity (BMI$40 kg/m2) are on the rise, and effective treatment options ar...
Objectives: To investigate associations of long-term nutrient intake, physical activity and obesity ...
Lifestyle interventions have resulted in weight loss or improved physical fitness among individuals ...
OBJECTIVE The impact of weight loss intervention on disability-free life expectancy in adults with d...
OBJECTIVE To determine whether an intensive lifestyle intervention (ILI) designed to sustain weight ...
Objective: To determine the effects of an intensive lifestyle intervention vs. a comparison group on...
Background Findings from the Look AHEAD trial showed no significant reductions in the primary outcom...
Importance: There is no definitive evidence that changes in physical activity/sedentary behavior can...
OBJECTIVE: Patients with type 2 diabetes are encouraged to lose weight, but excessive weight loss in...
Objectives: Physical fitness is related to all-cause mortality, quality of life and risk of falls in...
Aims/hypothesis The aim of this study was to evaluate the effects on diabetic peripheral neuropathy ...
OBJECTIVE: To assess the relative impact of an intensive lifestyle intervention (ILI) on use and cos...
The primary aims of this paper were (1) to evaluate the influence of intensive lifestyle weight loss...
Objective—To evaluate 8-year weight losses achieved with intensive lifestyle intervention (ILI) in t...
Background. Compared with adults without type 2 diabetes mellitus, those with the disease experience...
OBJECTIVEdRates of severe obesity (BMI$40 kg/m2) are on the rise, and effective treatment options ar...
Objectives: To investigate associations of long-term nutrient intake, physical activity and obesity ...
Lifestyle interventions have resulted in weight loss or improved physical fitness among individuals ...
OBJECTIVE The impact of weight loss intervention on disability-free life expectancy in adults with d...
OBJECTIVE To determine whether an intensive lifestyle intervention (ILI) designed to sustain weight ...
Objective: To determine the effects of an intensive lifestyle intervention vs. a comparison group on...
Background Findings from the Look AHEAD trial showed no significant reductions in the primary outcom...
Importance: There is no definitive evidence that changes in physical activity/sedentary behavior can...
OBJECTIVE: Patients with type 2 diabetes are encouraged to lose weight, but excessive weight loss in...
Objectives: Physical fitness is related to all-cause mortality, quality of life and risk of falls in...
Aims/hypothesis The aim of this study was to evaluate the effects on diabetic peripheral neuropathy ...
OBJECTIVE: To assess the relative impact of an intensive lifestyle intervention (ILI) on use and cos...
The primary aims of this paper were (1) to evaluate the influence of intensive lifestyle weight loss...