Add to ORKGWe discuss a recent Nature Medicine publication by Philip Johnson and co-workers (Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys. Nat. Med. 2009, 15: 901-906) in which an effective HIV-1 vaccine was designed that is based on gene therapy. The introduced gene produces an antibody-like immunoadhesin in the blood that neutralizes the virus. Commentary The current status of HIV vaccines The quest for a vaccine against the human immunodefi-ciency virus type 1 (HIV-1) has recently been given a bad prognosis [1]. Most attempts at developing an HIV-1 vac-cine have used substances (immunogens) aimed at stimu-lating the body's own immune system to produce antibodies or kil...
Development of a preventive vaccine for HIV is the best hope of controlling the AIDS pandemic. HIV ...
The extraordinary genetic diversity and immune evasion of human immunodeficiency virus (HIV) pose si...
A prophylactic vaccine for HIV-1 is badly needed. Despite 20 years of effort, it is still a long way...
ABSTRACT: We discuss a recent Nature Medicine publication by Philip Johnson and co-workers (Vector-m...
Lena J Gamble1, Qiana L Matthews1,21Division of Human Gene Therapy, Departments of Medicine, Patholo...
AbstractHuman immunodeficiency virus (HIV) is the cause of one of the most lethal pandemics in human...
Development of an effective AIDS vaccine is a global priority. However, the extreme diversity of HIV...
HIV/AIDS is a leading cause of mortality and morbidity worldwide. In spite of successful interventio...
Antibody gene transfer, which involves the delivery of genes that encode potent, broadly neutralizin...
The development of an effective HIV-1 vaccine must be considered as one of today s greatest biomedic...
While there has been remarkable progress in understanding the biology of HIV-1 and its recognition b...
Numerous human immunodeficiency virus (HIV)-1 vaccines have been developed over the last three decad...
Nearly 30 years have passed since the start of the global HIV epidemic and we are still unable to co...
The road to the discovery of a vaccine for HIV has been arduous and will continue to be difficult ov...
Enormous effort has been devoted to the development of a vaccine against human immunodeficiency viru...
Development of a preventive vaccine for HIV is the best hope of controlling the AIDS pandemic. HIV ...
The extraordinary genetic diversity and immune evasion of human immunodeficiency virus (HIV) pose si...
A prophylactic vaccine for HIV-1 is badly needed. Despite 20 years of effort, it is still a long way...
ABSTRACT: We discuss a recent Nature Medicine publication by Philip Johnson and co-workers (Vector-m...
Lena J Gamble1, Qiana L Matthews1,21Division of Human Gene Therapy, Departments of Medicine, Patholo...
AbstractHuman immunodeficiency virus (HIV) is the cause of one of the most lethal pandemics in human...
Development of an effective AIDS vaccine is a global priority. However, the extreme diversity of HIV...
HIV/AIDS is a leading cause of mortality and morbidity worldwide. In spite of successful interventio...
Antibody gene transfer, which involves the delivery of genes that encode potent, broadly neutralizin...
The development of an effective HIV-1 vaccine must be considered as one of today s greatest biomedic...
While there has been remarkable progress in understanding the biology of HIV-1 and its recognition b...
Numerous human immunodeficiency virus (HIV)-1 vaccines have been developed over the last three decad...
Nearly 30 years have passed since the start of the global HIV epidemic and we are still unable to co...
The road to the discovery of a vaccine for HIV has been arduous and will continue to be difficult ov...
Enormous effort has been devoted to the development of a vaccine against human immunodeficiency viru...
Development of a preventive vaccine for HIV is the best hope of controlling the AIDS pandemic. HIV ...
The extraordinary genetic diversity and immune evasion of human immunodeficiency virus (HIV) pose si...
A prophylactic vaccine for HIV-1 is badly needed. Despite 20 years of effort, it is still a long way...