Research Article Stability Studies of Thiocolchicoside in Bulk and Capsules Using RP-HPTLC/Densitometry

Copyright © 2013 Dnyansing K. Rajput et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. A new stability-indicating reversed-phase high-performance thin-layer chromatographic (RP-HPTLC) method for densitometric analysis of thiocolchicoside was developed and validated. The chromatograms were developed using aluminum plates pre-coated with silica gel 60 RP-18 F 254 S as a stationary phase and methanol: water (70: 30 v/v) as a mobile phase. The compact band for thiocolchicoside was observed a