Ab s t r a c t Introduction: Glucuronidation is an important phase II pathway responsible for the metabolism of many endogenous substances and drugs to less toxic metabo-lites, which undergo renal excretion. The aim of the current work was to eval-uate genotype and allele frequencies of certain UDP-glucuronosyltransferase 1A1 (UGT1A1) variants in an Arab population
Background: Pharmacogenetic studies on irinotecan treatment in patients with metastatic colorectal c...
Variation at the UDP-glucuronosyltransferase (UGT) 1A1 gene promoter is present in humans. Variable ...
The uridine diphosphate glucuronosyltransferase (UGT) 1A1 and 1A9 isoforms are involved in the phase...
AbstractGlucuronidation is an important phase II pathway responsible for many endogenous substances ...
Glucuronidation is an important phase II pathway responsible for many endogenous substances and drug...
Background: Genetic variation in glucuronosyltransferases (UGT) is crucial in drug metabolism and ri...
Aim: Uridine diphosphate glucuronosyltransferases (UGTs) are a superfamily of conjugation phase II e...
Glucuronidation by the uridine diphosphateglucuronosy-ltransferase 1A enzymes (UGT1As) is a major pa...
Over the past decade, the number of pharmacogenetic tests has increased considerably, allowing for t...
Cytochrome P450 (CYP450), sulfotransferase (SULT), and glucuronidase (UGT) enzymes play roles in the...
Cataloging interethnic differences in the distribution of genotypes of drug metabolic genes provides...
UDP-glucuronosyltransferases (UGTs) are phase II drug-metabolizing enzymes that metabolize endogenou...
go.jp) Glucuronidation, catalyzed by UDP-glucuronosyltrans-ferases (UGTs), is important in the detox...
Interindividual variability in polymorphic uridine diphosphate-glucuronosyltransferase 1A1 (UGT1A1) ...
Variation of a short (TA)(n) repeat sequence (rs8175347) covering the TATA box of UGT1A1 (UDP-glucur...
Background: Pharmacogenetic studies on irinotecan treatment in patients with metastatic colorectal c...
Variation at the UDP-glucuronosyltransferase (UGT) 1A1 gene promoter is present in humans. Variable ...
The uridine diphosphate glucuronosyltransferase (UGT) 1A1 and 1A9 isoforms are involved in the phase...
AbstractGlucuronidation is an important phase II pathway responsible for many endogenous substances ...
Glucuronidation is an important phase II pathway responsible for many endogenous substances and drug...
Background: Genetic variation in glucuronosyltransferases (UGT) is crucial in drug metabolism and ri...
Aim: Uridine diphosphate glucuronosyltransferases (UGTs) are a superfamily of conjugation phase II e...
Glucuronidation by the uridine diphosphateglucuronosy-ltransferase 1A enzymes (UGT1As) is a major pa...
Over the past decade, the number of pharmacogenetic tests has increased considerably, allowing for t...
Cytochrome P450 (CYP450), sulfotransferase (SULT), and glucuronidase (UGT) enzymes play roles in the...
Cataloging interethnic differences in the distribution of genotypes of drug metabolic genes provides...
UDP-glucuronosyltransferases (UGTs) are phase II drug-metabolizing enzymes that metabolize endogenou...
go.jp) Glucuronidation, catalyzed by UDP-glucuronosyltrans-ferases (UGTs), is important in the detox...
Interindividual variability in polymorphic uridine diphosphate-glucuronosyltransferase 1A1 (UGT1A1) ...
Variation of a short (TA)(n) repeat sequence (rs8175347) covering the TATA box of UGT1A1 (UDP-glucur...
Background: Pharmacogenetic studies on irinotecan treatment in patients with metastatic colorectal c...
Variation at the UDP-glucuronosyltransferase (UGT) 1A1 gene promoter is present in humans. Variable ...
The uridine diphosphate glucuronosyltransferase (UGT) 1A1 and 1A9 isoforms are involved in the phase...