Diffuse Interstitial Brain Edema in P Renal Disease Undergoing Hemo Spatial Statistics

Abstract: To investigate white matter (WM) alterations and their correlation with cognition function in end-stage renal disease (ESRD) patients undergoing hemodialysis (HD) using diffusion tensor imaging (DTI) with tract-based spatial statistics (TBSS) approach. This prospective HIPAA-complaint study was approved by our institutional review board. Eighty HD ESRD patients and 80 sex-and age-matched healthy controls were included. Neuropsychological (NP) tests and laboratory tests, including serum creatinine and urea, were performed. DTI data were processed to obtain fractional aniso-tropy (FA) and mean diffusivity (MD) maps with TBSS. FA and MD difference between the 2 groups were compared. We also explored the associatio tests, disea ESRD pat Comp the corpus ation, lef (P< 0.05, MD in H corrected) correlation correlation serum cre Diffus ruption oc dysfunctio changes. (Medicine Abbrev callosum imaging glomeru wise err diffusivi test typ thalamic radiata, al s-st sea lly-org lan ma m xim tive neg ban n ar is,7 lex edi itiv e n i