Copyright © 2014 Nadia Alfaidy et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Placentation is associated with several steps of vascular adaptations throughout pregnancy. These vascular changes occur both on thematernal and fetal sides, consisting ofmaternal uterine spiral arteries remodeling and placental vasculogenesis and angiogenesis, respectively. Placental angiogenesis is a pivotal process for efficient fetomaternal exchanges and placental development. This process is finely controlled throughout pregnancy, and it involves ubiquitous and pregnancy-specific angioge...