Add to ORKGIntroduction: Pressure ulcers are a prevalent health problem in today’s society. The shortage of suitable animal models limits our understanding and our ability to develop new therapies. This study aims to report on the development of a novel and reproducible human skin pressure ulcer model in mice. Material and Methods: Male non-obese, diabetic, severe combined immunodeficiency mice (n = 22) were engrafted with human skin. A full-thickness skin graft was placed onto 463 cm wounds created on the dorsal skin of the mice. Two group
Studies of skin graft behaviour in rodent excisional wound models are limited by the dominance of wo...
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease originating from the pilosebace...
The hypertrophic scar, a consequence of deep surface injury, is peculiar to humankind. Subcutaneous ...
INTRODUCTION: Pressure ulcers are a prevalent health problem in today's society. The shortage of sui...
Until the last two decades, research on the aetiology of pressure ulcers was primarily based on anim...
Until the last two decades, research on the aetiology of pressure ulcers was primarily based on anim...
Until the last two decades, research on the aetiology of pressure ulcers was primarily based on anim...
Until the last two decades, research on the aetiology of pressure ulcers was primarily based on anim...
Until the last two decades, research on the aetiology of pressure ulcers was primarily based on anim...
Until the last two decades, research on the aetiology of pressure ulcers was primarily based on anim...
<p>(A): Experimental design to generate the pressure-induced skin ulcer in mice. (B, C): Representat...
Cutaneous wound-healing disorders are a major health problem that requires the development of innova...
Contains fulltext : 108173.pdf (publisher's version ) (Open Access)Humanized mouse...
Numerous difficulties are associated with the conduct of preclinical studies related to skin and wou...
Advances in wound treatment depend on the availability of animal models that reflect key aspects of ...
Studies of skin graft behaviour in rodent excisional wound models are limited by the dominance of wo...
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease originating from the pilosebace...
The hypertrophic scar, a consequence of deep surface injury, is peculiar to humankind. Subcutaneous ...
INTRODUCTION: Pressure ulcers are a prevalent health problem in today's society. The shortage of sui...
Until the last two decades, research on the aetiology of pressure ulcers was primarily based on anim...
Until the last two decades, research on the aetiology of pressure ulcers was primarily based on anim...
Until the last two decades, research on the aetiology of pressure ulcers was primarily based on anim...
Until the last two decades, research on the aetiology of pressure ulcers was primarily based on anim...
Until the last two decades, research on the aetiology of pressure ulcers was primarily based on anim...
Until the last two decades, research on the aetiology of pressure ulcers was primarily based on anim...
<p>(A): Experimental design to generate the pressure-induced skin ulcer in mice. (B, C): Representat...
Cutaneous wound-healing disorders are a major health problem that requires the development of innova...
Contains fulltext : 108173.pdf (publisher's version ) (Open Access)Humanized mouse...
Numerous difficulties are associated with the conduct of preclinical studies related to skin and wou...
Advances in wound treatment depend on the availability of animal models that reflect key aspects of ...
Studies of skin graft behaviour in rodent excisional wound models are limited by the dominance of wo...
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease originating from the pilosebace...
The hypertrophic scar, a consequence of deep surface injury, is peculiar to humankind. Subcutaneous ...