Add to ORKGGenome-wide association studies (GWAS) are a laborious but powerful tool to identify genetic risk factors associated with complex polygenic traits such as obesity [1], diabetes [2], or coronary artery disease [3]. The link between genetic variation in FTO and obesity was first described in a GWAS for type 2 diabetes [1] and was later independently confirmed in different populations all over the world. First described in 2007, genetic variation in FTO has since become one of the most solidly confirmed risk factor for polygenic obesity in humans; yet, infor-mation about how FTO affects metabo
Until recently, progress in identification of the genetic variants influencing predisposition to com...
Large-scale genome-wide association studies (GWAS) have identified many loci associated with body ma...
Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity be...
Genome-wide association studies (GWAS) are a laborious but powerful tool to identify genetic risk fa...
In the 21st century, obesity has become a serious problem because of increasing obese patients and n...
GWAS have yielded many candidate loci for complex diseases like obesity, but interpreting the biolog...
Obesity is a serious international health problem that increases the risk of several common diseases...
Genome-wide association studies revealed that variants within FTO (fat-mass- and obesity-associated)...
In 2007, FTO was identified as the first genome-wide association study (GWAS) gene associated with o...
Obesity is a major health problem. Although heritability is substantial, genetic mechanisms predispo...
The fat mass and obesity-associated (FTO) gene was placed center stage when common intronic variants...
Obesity is a serious international health problem that increases the risk of several common diseases...
The fat mass and obesity-associated (FTO) gene was placed center stage when common intronic variants...
Obesity is a major health problem. Although heritability is substantial, genetic mechanisms predispo...
Obesity is a major public health problem with a significant genetic component. Multiple DNA polymorp...
Until recently, progress in identification of the genetic variants influencing predisposition to com...
Large-scale genome-wide association studies (GWAS) have identified many loci associated with body ma...
Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity be...
Genome-wide association studies (GWAS) are a laborious but powerful tool to identify genetic risk fa...
In the 21st century, obesity has become a serious problem because of increasing obese patients and n...
GWAS have yielded many candidate loci for complex diseases like obesity, but interpreting the biolog...
Obesity is a serious international health problem that increases the risk of several common diseases...
Genome-wide association studies revealed that variants within FTO (fat-mass- and obesity-associated)...
In 2007, FTO was identified as the first genome-wide association study (GWAS) gene associated with o...
Obesity is a major health problem. Although heritability is substantial, genetic mechanisms predispo...
The fat mass and obesity-associated (FTO) gene was placed center stage when common intronic variants...
Obesity is a serious international health problem that increases the risk of several common diseases...
The fat mass and obesity-associated (FTO) gene was placed center stage when common intronic variants...
Obesity is a major health problem. Although heritability is substantial, genetic mechanisms predispo...
Obesity is a major public health problem with a significant genetic component. Multiple DNA polymorp...
Until recently, progress in identification of the genetic variants influencing predisposition to com...
Large-scale genome-wide association studies (GWAS) have identified many loci associated with body ma...
Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity be...