Add to ORKGLong-term proteasomal inhibition in transgenic mice by UBB+1 expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patient
Alzheimer's disease is the most common form of dementia and is characterised by an accumulation of p...
Covalent linkage of ubiquitin regulates the function and, ultimately, the degradation of many protei...
UBB+1, a mutant form of ubiquitin, is both a substrate and an inhibitor of the proteasome which accu...
Aging and neurodegeneration are often accompanied by a functionally impaired ubiquitin-proteasome sy...
Aging and neurodegeneration are often accompanied by a functionally impaired ubiquitin-proteasome sy...
Contains fulltext : 153294.pdf (publisher's version ) (Open Access)Loss of protein...
proteasome inhibition triggers neurodegeneration in a transgenic mouse model expressing human a-synu...
Amyloid-beta (Ab) plaques are a prominent pathological hallmark of Alzheimer's disease (AD). They co...
The ubiquitin-proteasome system fulfills a pivotal role in regulating intracellular protein turnover...
Amyloid-β (Aβ) plaques are a prominent pathological hallmark of Alzheimer's disease (AD). They consi...
<p>The ubiquitin-proteasome system (UPS) is the main pathway responsible for the degradation of misf...
The mutant ubiquitin UBB+1 is a substrate as well as an inhibitor of the ubiquitin-proteasome system...
Alzheimer disease (AD) is a progressive neurodegenerative disorder and the most common type of demen...
Alzheimer's disease is the most common form of dementia and is characterised by an accumulation of p...
Covalent linkage of ubiquitin regulates the function and, ultimately, the degradation of many protei...
UBB+1, a mutant form of ubiquitin, is both a substrate and an inhibitor of the proteasome which accu...
Aging and neurodegeneration are often accompanied by a functionally impaired ubiquitin-proteasome sy...
Aging and neurodegeneration are often accompanied by a functionally impaired ubiquitin-proteasome sy...
Contains fulltext : 153294.pdf (publisher's version ) (Open Access)Loss of protein...
proteasome inhibition triggers neurodegeneration in a transgenic mouse model expressing human a-synu...
Amyloid-beta (Ab) plaques are a prominent pathological hallmark of Alzheimer's disease (AD). They co...
The ubiquitin-proteasome system fulfills a pivotal role in regulating intracellular protein turnover...
Amyloid-β (Aβ) plaques are a prominent pathological hallmark of Alzheimer's disease (AD). They consi...
<p>The ubiquitin-proteasome system (UPS) is the main pathway responsible for the degradation of misf...
The mutant ubiquitin UBB+1 is a substrate as well as an inhibitor of the ubiquitin-proteasome system...
Alzheimer disease (AD) is a progressive neurodegenerative disorder and the most common type of demen...
Alzheimer's disease is the most common form of dementia and is characterised by an accumulation of p...
Covalent linkage of ubiquitin regulates the function and, ultimately, the degradation of many protei...
UBB+1, a mutant form of ubiquitin, is both a substrate and an inhibitor of the proteasome which accu...