© 2015 Saudi Journal of Gastroenterology (Official journal of The Saudi Gastroenterology Association) Published by Wolters Kluwer- Medknow The New Era of Hepatitis C Virus Therapy

com The hepatitis C virus (HCV) has a significant medical and economic impact on societies around the world, and it has been estimated that 130-180 million people are infected with HCV. Therapies for HCV are currently undergoing a revolution. In recent years, several new treatments have been approved by the United States Food and Drug Administration, and many other treatments are in phase II or III clinical trials, including direct antiviral agents (DAAs). Due to recent major advances in the field of HCV therapy, a summary of findings on new HCV therapies are provided in this review article, including reports on new DAAs. Key Words: Cirrhosis and null responders, direct antiviral agents, hepatitis C viru