Add to ORKGCopyright © 2015 Jing Sun et al.This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Protein tyrosine phosphatase 1B (PTP1B) is an established therapeutic target for type 2 diabetes mellitus (T2DM) and obesity. The aim of this study was to investigate the inhibitory activity ofMagnolia officinalis extract (ME) on PTP1B and its anti-T2DM effects. Inhibition assays and inhibition kinetics of ME were performed in vitro. 3T3-L1 adipocytes and C2C12 myotubes were stimulated with ME to explore its bioavailability in cell level. The in vivo studies were performed on db/db mice to probe it...
which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
Diabetes has increased radically in recent decades globally. Diabetes mainly emerged as a major heal...
Protein tyrosine phosphatase 1B (PTP1B) is an intracellular enzyme responsible for deactivation of t...
Protein tyrosine phosphatase 1B (PTP1B) is an established therapeutic target for type 2 diabetes mel...
which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
This data article contains data related to the research article entitled “Fumosorinone, a novel PTP1...
AbstractThis data article contains data related to the research article entitled “Fumosorinone, a no...
Copyright © 2014 Makoto Ito et al. This is an open access article distributed under the Creative Com...
Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, p...
Many biologically active polyphenols have been recognized for their beneficial effects in managing d...
Background: Augmenting glucose utilization in skeletal muscle via the phosphatidylinositol-3 kinase ...
Starting off with a structure derived from the natural compound multiflorine, a derivatisation progr...
Butterfly pea (Clitoria ternatea) is an indigenous plant from Moluccas in Indonesia. Due to its phar...
Background: Protein tyrosine phosphatase (PTP) 1B, a negative regulator of the insulin and leptin si...
The data presented in this article are related to the research article under the title “in vitro ant...
which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
Diabetes has increased radically in recent decades globally. Diabetes mainly emerged as a major heal...
Protein tyrosine phosphatase 1B (PTP1B) is an intracellular enzyme responsible for deactivation of t...
Protein tyrosine phosphatase 1B (PTP1B) is an established therapeutic target for type 2 diabetes mel...
which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
This data article contains data related to the research article entitled “Fumosorinone, a novel PTP1...
AbstractThis data article contains data related to the research article entitled “Fumosorinone, a no...
Copyright © 2014 Makoto Ito et al. This is an open access article distributed under the Creative Com...
Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, p...
Many biologically active polyphenols have been recognized for their beneficial effects in managing d...
Background: Augmenting glucose utilization in skeletal muscle via the phosphatidylinositol-3 kinase ...
Starting off with a structure derived from the natural compound multiflorine, a derivatisation progr...
Butterfly pea (Clitoria ternatea) is an indigenous plant from Moluccas in Indonesia. Due to its phar...
Background: Protein tyrosine phosphatase (PTP) 1B, a negative regulator of the insulin and leptin si...
The data presented in this article are related to the research article under the title “in vitro ant...
which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
Diabetes has increased radically in recent decades globally. Diabetes mainly emerged as a major heal...
Protein tyrosine phosphatase 1B (PTP1B) is an intracellular enzyme responsible for deactivation of t...