Exposure to inorganic arsenic increases the risk of basal cell carcinoma (BCC). Arsenic metabolism is a susceptibility factor for arsenic toxicity, and specific haplotypes in arsenic (13 oxidation state) methyl-transferase (AS3MT) have been associated with increased urinary fractions of the most toxic arsenic metabolite, methylarsonic acid (MMA). The aim of this study is to elucidate the association of AS3MT haplotypes with arsenic metabolism and the risk of BCC. FourAS3MT polymorphismswere genotyped in BCC cases (N5529) and controls (N5533) from Eastern Europewith low tomoderate arsenic exposure (lifetime average drinking water concentration: 1.3 mg/L, range 0.01–167 mg/L). Urinary metabolites [inorganic arsenic (iAs), MMA, dimethylarsinic...
The susceptibility to arsenic-induced diseases differs greatly between individuals, possibly due to ...
Abstract Background Ingestion of groundwater with high concentrations of inorganic arsenic has been ...
<div><p>Arsenic is a very potent toxicant. One major susceptibility factor for arsenic-related toxic...
Exposure to inorganic arsenic increases the risk of basal cell carcinoma (BCC). Arsenic metabolism i...
OBJECTIVES: The susceptibility to arsenic (As)-induced diseases differs greatly between individuals,...
Background: Arsenic is mono- (MMA) and dimethylated (DMA) in humans and the methylation pattern demo...
Arsenic, a ubiquitous metalloid, is one of the most com-coronary heart disease, hypertension, arteri...
Inorganic arsenic (iAs) is a recognized environment-related factor for bladder cancer (BCa). Arsenic...
Background: Exposure to arsenic (As) is associated with an increased risk of several cancers as well...
<div><p>Arsenic contamination of drinking water is a major public health issue in many countries, in...
Methylation is the primary route of metabolism of inorganic arsenic in humans, and previous studies ...
Chronic environmental exposure to inorganic arsenic is widely associated with human disease. Low hum...
Abstract: Incomplete arsenic (As) methylation has been considered a risk factor of As-related diseas...
Lung cancer is the most common neoplasm and the primary cause-related mortality in developed and in ...
Arsenic is a very potent toxicant. One major susceptibility factor for arsenic-related toxicity is t...
The susceptibility to arsenic-induced diseases differs greatly between individuals, possibly due to ...
Abstract Background Ingestion of groundwater with high concentrations of inorganic arsenic has been ...
<div><p>Arsenic is a very potent toxicant. One major susceptibility factor for arsenic-related toxic...
Exposure to inorganic arsenic increases the risk of basal cell carcinoma (BCC). Arsenic metabolism i...
OBJECTIVES: The susceptibility to arsenic (As)-induced diseases differs greatly between individuals,...
Background: Arsenic is mono- (MMA) and dimethylated (DMA) in humans and the methylation pattern demo...
Arsenic, a ubiquitous metalloid, is one of the most com-coronary heart disease, hypertension, arteri...
Inorganic arsenic (iAs) is a recognized environment-related factor for bladder cancer (BCa). Arsenic...
Background: Exposure to arsenic (As) is associated with an increased risk of several cancers as well...
<div><p>Arsenic contamination of drinking water is a major public health issue in many countries, in...
Methylation is the primary route of metabolism of inorganic arsenic in humans, and previous studies ...
Chronic environmental exposure to inorganic arsenic is widely associated with human disease. Low hum...
Abstract: Incomplete arsenic (As) methylation has been considered a risk factor of As-related diseas...
Lung cancer is the most common neoplasm and the primary cause-related mortality in developed and in ...
Arsenic is a very potent toxicant. One major susceptibility factor for arsenic-related toxicity is t...
The susceptibility to arsenic-induced diseases differs greatly between individuals, possibly due to ...
Abstract Background Ingestion of groundwater with high concentrations of inorganic arsenic has been ...
<div><p>Arsenic is a very potent toxicant. One major susceptibility factor for arsenic-related toxic...