Recently, defense peptides that are able to act against several targets have been characterized. The present work focuses on structural and functional evaluation of the peptide analogue Pa-MAP, previously isolated as an antifreeze peptide from Pleuronectes americanus. Pa-MAP showed activities against different targets such as tumoral cells in culture (CACO-2, MCF-7 and HCT-116), bacteria (Escherichia coli ATCC 8739 and Staphylococcus aureus ATCC 25923), viruses (HSV-1 and HSV-2) and fungi (Candida parapsilosis ATCC 22019, Trichophyton mentagrophytes (28d&E) and T. rubrum (327)). This peptide did not show toxicity against mammalian cells such as erythrocytes, Vero and RAW 264.7 cells. Molecular mechanism of action was related to hydropho...
Cationic antimicrobial peptides (CAMPs) are a promising alternative to treat multidrug-resistant bac...
Abstract Given the widespread demand for novel antibacterial agents, we modified a cell-penetrating ...
Antimicrobial peptides occur in a diverse range of organisms from microorganisms to insects, plants ...
Recently, defense peptides that are able to act against several targets have been characterized. The...
<div><p>Recently, defense peptides that are able to act against several targets have been characteri...
© 2016 Published by Elsevier B.V.Recently, several peptides have been studied regarding the defence ...
AbstractIn several organisms, the first barrier against microbial infections consists of antimicrobi...
Thousands of antimicrobial peptides (AMPs) of prokaryotic, fungal, plant, or animal origin have been...
AbstractAs fundamental components in innate immunity, antimicrobial peptides (AMPs) hold great poten...
The excessive use of antibiotics, which has led to multi-resistant bacteria, makes it necessary to d...
This work is licensed under a Creative Commons Attribution 4.0 International License. The images or...
The incidence of antibiotic resistance amongst bacteria has increased steadily due to the over presc...
Antimicrobial peptides represent a heterogeneous group that displays multiple modes of action such a...
The continued emergence of new antibiotic resistant bacterial strains has resulted in great interest...
In recent years, antimicrobial peptides isolated from amphibian toxins have gained attention as new ...
Cationic antimicrobial peptides (CAMPs) are a promising alternative to treat multidrug-resistant bac...
Abstract Given the widespread demand for novel antibacterial agents, we modified a cell-penetrating ...
Antimicrobial peptides occur in a diverse range of organisms from microorganisms to insects, plants ...
Recently, defense peptides that are able to act against several targets have been characterized. The...
<div><p>Recently, defense peptides that are able to act against several targets have been characteri...
© 2016 Published by Elsevier B.V.Recently, several peptides have been studied regarding the defence ...
AbstractIn several organisms, the first barrier against microbial infections consists of antimicrobi...
Thousands of antimicrobial peptides (AMPs) of prokaryotic, fungal, plant, or animal origin have been...
AbstractAs fundamental components in innate immunity, antimicrobial peptides (AMPs) hold great poten...
The excessive use of antibiotics, which has led to multi-resistant bacteria, makes it necessary to d...
This work is licensed under a Creative Commons Attribution 4.0 International License. The images or...
The incidence of antibiotic resistance amongst bacteria has increased steadily due to the over presc...
Antimicrobial peptides represent a heterogeneous group that displays multiple modes of action such a...
The continued emergence of new antibiotic resistant bacterial strains has resulted in great interest...
In recent years, antimicrobial peptides isolated from amphibian toxins have gained attention as new ...
Cationic antimicrobial peptides (CAMPs) are a promising alternative to treat multidrug-resistant bac...
Abstract Given the widespread demand for novel antibacterial agents, we modified a cell-penetrating ...
Antimicrobial peptides occur in a diverse range of organisms from microorganisms to insects, plants ...