Med Oral Patol Oral Cir Bucal. 2015 Sep 1;20 (5):e554-9. Diode laser and pseudoepitheliomatous hyperplasia e554 Journal section: Oral Medicine and Pathology Publication Types: Research

Background: To examine the process of epithelial reparation in a surgical wound caused by diode laser. Material and Methods: An experimental study with 27 Sprage-Dawley rats was undertaken. The animals were randomly allocated to two experimental groups, whose individuals underwent glossectomy by means of a diode laser at different wattages, and a control group treated using a number 15 scalpel blade. The animals were slaughtered at the 2nd, 7th, and 14th day after glossectomy. The specimens were independently studied by two pathologists (blinded for the specimens ’ group). Results: At the 7th day, re-epithelisation was slightly faster for the control group (conventional scalpel) (p=0.011). At the 14th day, complete re-epithelization was observed for all groups. The experimental groups displayed a pseudoepitheliomatous hyperplasia. Conclusions: It is concluded that, considering the limitations of this kind of experimental studies, early re-epithe-lisation occurs slightly faster when a conventional scalpel is used for incision, although re-epithelisation is com-pleted in two weeks no matter the instrument used. In addition, pseudoepitheliomatous hyperplasia is a potential event after oral mucosa surgery with diode laser. Knowledge about this phenomenon (not previously described