Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Extracellular nucleotides are ubiquitous signalling molecules which modulate distinct physiological and pathological processes. Nucleotide concentrations in the extracellular space are strictly regulated by cell surface enzymes, called ectonucleotidases, which hydrolyze nucleotides to the respective nucleosides. Recent studies suggest that ectonucleotidases play a significant role in inflammation by adjusting the balance between ATP, a widely distributed proinflammatory danger signal, and the anti-inflammatory mediator adenosine. There is increasing evidence for a central role of adenosine in alloa...
There is increasing evidence showing that extracellular nucleosides [corrected] may be important med...
which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
Danger signals released upon cell damage can cause excessive immune-mediated tissue destruction like...
Extracellular adenosine is a potent immunomodulatory molecule that accumulates in states of inflamma...
When present in the extracellular environment, the nucleoside adenosine protects cells and tissues f...
Purinergic signaling has been recognized as playing an important role in inflammation, angiogenesis,...
Extracellular nucleotides (e.g. ATP, UTP, ADP) are released by activated endothelium, leukocytes and...
Ectonucleotidases are extracellular enzymes with a pivotal role in inflammation that hydrolyse extra...
Artículo de publicación ISIExtracellular ATP is a danger signal released by dying and damaged cells,...
Purinergic signaling modulates systemic and local inflammatory responses. Extracellular nucleotides,...
ATP and its ultimate degradation product adenosine are potent extracellular signalling molecules tha...
AbstractExtracellular ATP is a danger signal released by dying and damaged cells, and it functions a...
Abstract The purinergic signalling system comprises extracellular nucleotides such as adenosine trip...
Copyright © 2015 Jean Sévigny et al. This is an open access article distributed under the Creative ...
The ectonucleotidases CD39 and CD73 hydrolyze extracellular adenosine triphosphate (ATP) and adenosi...
There is increasing evidence showing that extracellular nucleosides [corrected] may be important med...
which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
Danger signals released upon cell damage can cause excessive immune-mediated tissue destruction like...
Extracellular adenosine is a potent immunomodulatory molecule that accumulates in states of inflamma...
When present in the extracellular environment, the nucleoside adenosine protects cells and tissues f...
Purinergic signaling has been recognized as playing an important role in inflammation, angiogenesis,...
Extracellular nucleotides (e.g. ATP, UTP, ADP) are released by activated endothelium, leukocytes and...
Ectonucleotidases are extracellular enzymes with a pivotal role in inflammation that hydrolyse extra...
Artículo de publicación ISIExtracellular ATP is a danger signal released by dying and damaged cells,...
Purinergic signaling modulates systemic and local inflammatory responses. Extracellular nucleotides,...
ATP and its ultimate degradation product adenosine are potent extracellular signalling molecules tha...
AbstractExtracellular ATP is a danger signal released by dying and damaged cells, and it functions a...
Abstract The purinergic signalling system comprises extracellular nucleotides such as adenosine trip...
Copyright © 2015 Jean Sévigny et al. This is an open access article distributed under the Creative ...
The ectonucleotidases CD39 and CD73 hydrolyze extracellular adenosine triphosphate (ATP) and adenosi...
There is increasing evidence showing that extracellular nucleosides [corrected] may be important med...
which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
Danger signals released upon cell damage can cause excessive immune-mediated tissue destruction like...