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www.cmj.hr Aim To gain insight into the relations between protective/ risk family interactions and depressive symptoms in ado-lescent boys and girls. Method A self-reported cross-sectional survey was con-ducted on a representative sample of 1191 secondary school students (617 girls and 574 boys) aged from 14 to 19 years, with a median of 16, from all secondary schools in the Primorsko-goranska County, Croatia in January and February 2010. Students reported their depressive symp-toms, perceptions about the relationship with their moth-er and father, family activities, and parents ’ conflict resolu-tion strategies. Data were analyzed by hierarchical multiple regression to calculate the effects of family supportive and harmful interactions on depressive symptoms in girls an