Mycophenolic acid (MPA) is the metabolized product and active element of mycophenolate mofetil (MMF) that has been widely used for the prevention of acute graft rejection. MPA potently inhibits inosine monophosphate dehydrogenase (IMPDH) that is up-regulated in many tumors and MPA is known to inhibit cancer cell proliferation as well as fibroblast and endothelial cell migration. In this study, we demonstrated for the first time MPA’s antimigratory and anti-invasion abilities of MPA-sensitive AGS (gastric cancer) cells. Genome-wide expression analyses using Illumina whole genome microarrays identified 50 genes with ≥2 fold changes and 15 genes with> 4 fold alterations and multiple molecular pathways implicated in cell migration. Real-time...
Dan Sun, Yiwei Wang, Shanshan Jiang, Gang Wang, Yan Xin Laboratory of Gastrointestinal Onco-Patholo...
BACKGROUND: We previously found that docosahexaenoic acid (DHA), a dietary polyunsaturated fatty aci...
Patients with pancreatic ductal adenocarcinoma (PC) have a poor prognosis due to metastases and chem...
Mycophenolic acid (MPA) is the metabolized product and active element of mycophenolate mofetil (MMF)...
Mycophenolic acid (MPA) is prescribed to maintain allografts in organ-transplanted patients. However...
Mycophenolic acid (MPA) is prescribed to maintain allografts in organ-transplanted patients. However...
Xiang Zhou,1 Zhu-juan Xiong,2 Shuo-meng Xiao,1 Jin Zhou,3 Zhi Ding,1 Ling-chao Tang,1 Xiao-dong Chen...
Item does not contain fulltextMycophenolic acid is the active ingredient of the immunosuppressant my...
Mycophenolic acid is the active ingredient of the immunosuppressant mycophenolate mofetil that is wi...
[[abstract]]Cell motility involves metastasis suppressors and other regulators that play an importan...
L'acido micofenolico (MPA) è una micotossina nota per la sue proprietà antibiotiche, anti-neoplastic...
Mycophenolic acid (MPA), the active metabolite of myco-phenolate mofetil (MMF), is being used increa...
Breast cancer is one of the most prevalent cancers in women, and nearly half of breast cancer patien...
Mycophenolate mofetil (MMF) is the ester prodrug of mycophenolic acid (MPA), produced by Penicillium...
Metastasis is a major cause of death in patients with breast cancer. In the process of cancer develo...
Dan Sun, Yiwei Wang, Shanshan Jiang, Gang Wang, Yan Xin Laboratory of Gastrointestinal Onco-Patholo...
BACKGROUND: We previously found that docosahexaenoic acid (DHA), a dietary polyunsaturated fatty aci...
Patients with pancreatic ductal adenocarcinoma (PC) have a poor prognosis due to metastases and chem...
Mycophenolic acid (MPA) is the metabolized product and active element of mycophenolate mofetil (MMF)...
Mycophenolic acid (MPA) is prescribed to maintain allografts in organ-transplanted patients. However...
Mycophenolic acid (MPA) is prescribed to maintain allografts in organ-transplanted patients. However...
Xiang Zhou,1 Zhu-juan Xiong,2 Shuo-meng Xiao,1 Jin Zhou,3 Zhi Ding,1 Ling-chao Tang,1 Xiao-dong Chen...
Item does not contain fulltextMycophenolic acid is the active ingredient of the immunosuppressant my...
Mycophenolic acid is the active ingredient of the immunosuppressant mycophenolate mofetil that is wi...
[[abstract]]Cell motility involves metastasis suppressors and other regulators that play an importan...
L'acido micofenolico (MPA) è una micotossina nota per la sue proprietà antibiotiche, anti-neoplastic...
Mycophenolic acid (MPA), the active metabolite of myco-phenolate mofetil (MMF), is being used increa...
Breast cancer is one of the most prevalent cancers in women, and nearly half of breast cancer patien...
Mycophenolate mofetil (MMF) is the ester prodrug of mycophenolic acid (MPA), produced by Penicillium...
Metastasis is a major cause of death in patients with breast cancer. In the process of cancer develo...
Dan Sun, Yiwei Wang, Shanshan Jiang, Gang Wang, Yan Xin Laboratory of Gastrointestinal Onco-Patholo...
BACKGROUND: We previously found that docosahexaenoic acid (DHA), a dietary polyunsaturated fatty aci...
Patients with pancreatic ductal adenocarcinoma (PC) have a poor prognosis due to metastases and chem...