POSTER PRESENTATION Open Access Effects of neuronal adaptation currents on

Local field potential in-vivo recordings often show oscilla-tions with frequencies ranging from < 1 Hz to 100 Hz. The underlying mechanism could change across frequency bands but likely involves network interactions such as recurrent synaptic excitation-inhibition loops. Particularly fast rhythmic activity in the beta and gamma range is thought to be caused by synaptic inhibition [1]. Although these oscillations primarily depend on synaptic properties, their frequency is significantly influenced by the passive membrane characteristics of single cells [2]. In addition, neuronal membranes typically contain slowly deactivating voltage-dependent as well as calcium-activated potassium channels both which mediate spike rate adaptation. Here we investigate how the dynamics of such neuronal adaptation currents contribute to synaptically generate