ORIGINAL ARTICLE

liver cancer, and gastric cancer.1 Foods originated from animals, genetic factors, and IBDs are being known as important risk factors for colon cancer. Life style factors such as alcohol consumption as well as smoking may affect colon cancer, but it is still controversial with a paucity of studies.2-4 It has not been clearly established regarding the relation-ship between alcohol consumption and colorectal adenoma, yet there are several studies describing that alcohol intake impacts on the development of colorectal adenoma.2,5 In order to estimate the amount of alcohol consumption, it was often relying on interviewing but it lacks accuracy and ac-companies inter-individual variability considering its nature thereby making it difficult to elucidate exact roles of alcohol intake in reference to colorectal adenoma development. In the current study, we investigated effects of alcohol intak