RETRACTION Retraction: RNAi-Dependent and Independent Control of LINE1 Accumulation and Mobility in Mouse Embryonic Stem Cells

At the request of the authors, PLOS Genetics is retracting this publication following an investi-gation into concerns that were raised regarding the assembly of Fig 4 and S4 Fig, and the statis-tical analysis used in Fig 2A. The text below has been agreed to by the authors and editors. The corresponding author, Olivier Voinnet, was originally alerted to errors that occurred during the assembly of Fig 4 (panel A) and S4 Fig (panels A and F). These errors have been cor-rected using the original raw data, and a correction notice was published accordingly. Further analysis of the paper revealed flaws in the interpretation of the transposition data presented in Fig 2A. In the originally submitted version, the L1 copy number was only pre-sented for the DCRFlx/Flx P10 and DCR-/- P30 cells, and a T-test performed on the two datasets showed that the L1 copy number was statistically higher in DCR-/- cells than in control cells. During the last stage of the review process, additional datasets were added and a second T-test was then used to establish the statistical analysis published in the final version of the paper. However, it was later realized that T-tests are not appropriate for comparing more than two datasets. At the recommendation of the ETH statistics helpdesk, a suitable Analysis of Variance (ANOVA) test with multiple comparisons was then conducted on the DcrFlx/Flx P30 and Dcr-/